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Transcatheter Aortic Valve Replacement: State of the Art and Future Directions
Annual Review of Medicine ( IF 15.1 ) Pub Date : 2017-01-18 00:00:00 , DOI: 10.1146/annurev-med-101615-020427
Mackram F. Eleid 1 , David R. Holmes 1
Affiliation  

Transcatheter aortic valve replacement (TAVR) is a transformational and rapidly evolving treatment for patients with aortic stenosis who require valve replacement. Novel technological advancements have made this percutaneous minimally invasive therapy a first-line treatment for many patients at extreme risk for conventional cardiac surgery. New devices and improvements in existing devices have reduced procedural complications, and scientific trials are investigating the role of TAVR in lower-risk aortic stenosis populations, in patients with aortic regurgitation, and in patients with bicuspid aortic valve disease. Finally, there is intense interest in identifying patients in whom the risk-benefit ratio of TAVR is not favorable and should not be performed.

中文翻译:


经导管主动脉瓣置换术:最新发展和未来方向

经导管主动脉瓣置换术(TAVR)是一种需要快速更换瓣膜的主动脉瓣狭窄患者的变革性和快速发展的治疗方法。新颖的技术进步已使这种经皮微创治疗成为许多常规心脏手术极高风险患者的一线治疗。新设备和对现有设备的改进减少了手术并发症,科学试验正在研究TAVR在低风险主动脉瓣狭窄人群,主动脉瓣关闭不全患者和二尖瓣主动脉瓣膜疾病中的作用。最后,人们非常关注识别TAVR的风险收益率不理想且不应进行的患者。

更新日期:2017-01-18
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