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Structure and Function of the Mitochondrial Ribosome
Annual Review of Biochemistry ( IF 12.1 ) Pub Date : 2016-06-13 00:00:00 , DOI: 10.1146/annurev-biochem-060815-014343
Basil J. Greber 1, 2 , Nenad Ban 1
Affiliation  

Mitochondrial ribosomes (mitoribosomes) perform protein synthesis inside mitochondria, the organelles responsible for energy conversion and adenosine triphosphate production in eukaryotic cells. Throughout evolution, mitoribosomes have become functionally specialized for synthesizing mitochondrial membrane proteins, and this has been accompanied by large changes to their structure and composition. We review recent high-resolution structural data that have provided unprecedented insight into the structure and function of mitoribosomes in mammals and fungi.

中文翻译:


线粒体核糖体的结构和功能

线粒体核糖体(线粒体)在线粒体内进行蛋白质合成,线粒体是负责真核细胞中能量转换和三磷酸腺苷生成的细胞器。在整个进化过程中,线粒体已在功能上专门用于合成线粒体膜蛋白,并且伴随其结构和组成的巨大变化。我们审查了最近的高分辨率结构数据,这些数据为哺乳动物和真菌中的线粒体的结构和功能提供了空前的见识。

更新日期:2016-06-13
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