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The Dynamic Identity of Intestinal Cancer Stem Cells
Cell Stem Cell ( IF 19.8 ) Pub Date : 2017-06-01 00:00:00 , DOI: 10.1016/j.stem.2017.05.018
Piero Dalerba

Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate malignant tissues. In a recent article inNature, de Sousa e Melo et al. (2017) reveal that intestinal tumors can contain dynamic pools of functionally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironment.

中文翻译:

肠癌干细胞的动态身份

要永久根除恶性组织,必须消除自我更新的癌症干细胞(CSC)。在《自然》杂志的最新文章中,de Sousa e Melo等人。(2017)发现肠道肿瘤可以包含功能上不同的CSC种群的动态库,这些宿主似乎可以根据宿主组织的微环境进行相互转化。
更新日期:2017-06-12
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