Anti-tumour necrosis factor (TNF) antibodies represent established therapies for inflammatory bowel disease (IBD), but up to 40% of patients exhibit primary nonresponsiveness to anti-TNF agents, and resistance can develop. West et al. observe high levels of the cytokine oncostatin M (OSM) and its receptor

中文翻译：

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炎症：抑癌素M阻断可减轻结肠炎

抗肿瘤坏死因子（TNF）抗体代表了炎性肠病（IBD）的既定疗法，但多达40％的患者对抗TNF药物表现出主要的无反应性，并且会产生耐药性。韦斯特等。观察到高水平的细胞因子抑制素M（OSM）及其受体