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Cystic fibrosis: Thymosin α1 rescues CFTR activity
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-05-31 , DOI: 10.1038/nrd.2017.99
Sarah Crunkhorn

Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein and is characterized by chronic lung inflammation. Romani et al. show that the naturally occurring polypeptide thymosin α1 — clinically used as an immunotherapeutic agent —

中文翻译:

囊性纤维化:胸腺素α1可拯救CFTR活性

囊性纤维化是由编码囊性纤维化跨膜电导调节剂(CFTR)蛋白的基因突变引起的,其特征是慢性肺部炎症。罗曼尼(Romani)等人。表明天然存在的多肽胸腺素α1(临床上被用作免疫治疗剂)
更新日期:2017-05-31
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