Globalization has driven new paradigms for drug discovery and development. Activities previously carried out predominantly in the United States, Europe, and Japan are now carried out globally. This has caused considerable change in large pharma including how medicinal chemists are trained. Described here is the training of chemistry undergraduates in medicinal chemistry (as practiced in industry) in two modules developed in collaboration between the University of Nottingham (UoN) and GlaxoSmithKline (GSK). The students complete several design–synthesize–test iterations on medicinal chemistry projects where they carry out the design and synthesis, and GSK tests the compounds. Considerable emphasis is placed on standard design properties used within industry. The modules are popular with the students and usually oversubscribed. An unexpected benefit has been the opportunities that have emerged with research and commercial potential. Graduate and postgraduate training of medicinal chemists at GSK is also briefly described.

中文翻译：

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在学术界和工业界的合作中不寻常的药物化学本科培训

全球化推动了药物发现和开发的新范式。以前主要在美国、欧洲和日本开展的活动现在在全球开展。这导致大型制药公司发生了相当大的变化，包括药物化学家的培训方式。这里描述的是在诺丁汉大学 (UoN) 和葛兰素史克 (GSK) 合作开发的两个模块中对化学本科生进行药物化学（工业实践）的培训。学生们在药物化学项目中完成了几次设计-合成-测试迭代，他们在这些项目中进行设计和合成，GSK 对化合物进行测试。相当重视工业中使用的标准设计属性。这些模块很受学生欢迎，并且通常被超额订阅。一个意想不到的好处是出现了具有研究和商业潜力的机会。还简要介绍了葛兰素史克药物化学家的研究生和研究生培训。