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G protein-coupled receptors: Novel probe for MRGPRX2
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-04-18 00:00:00 , DOI: 10.1038/nrd.2017.77 Crunkhorn Sarah
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-04-18 00:00:00 , DOI: 10.1038/nrd.2017.77 Crunkhorn Sarah
The orphan MAS-related G protein-coupled receptor member X2 (MRGPRX2) is expressed primarily in human dorsal root ganglia and mast cells, and has been suggested to modulate pain and itch. Using a high-throughput screen of 5,695 unique compounds, Lansu et al. discovered that many exogenous
中文翻译:
G蛋白偶联受体:MRGPRX2的新型探针
孤儿与MAS相关的G蛋白偶联受体成员X2(MRGPRX2)主要在人背根神经节和肥大细胞中表达,并已被认为可调节疼痛和瘙痒。Lansu等人使用5695种独特化合物的高通量筛选。发现很多外生的
更新日期:2017-05-18
中文翻译:
G蛋白偶联受体:MRGPRX2的新型探针
孤儿与MAS相关的G蛋白偶联受体成员X2(MRGPRX2)主要在人背根神经节和肥大细胞中表达,并已被认为可调节疼痛和瘙痒。Lansu等人使用5695种独特化合物的高通量筛选。发现很多外生的