Invasive fungal infections are a major medical concern, particularly in immunocompromised patients. In this Review, Perfect discusses the antifungal pipeline, including advances in the currently used drug classes, novel molecular targets, drugs that could be repurposed from other areas and the use of immune-directed therapies.

中文翻译：

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抗真菌药物管道：现实检查

侵袭性真菌感染是主要的医学问题，尤其是在免疫功能低下的患者中。在本综述中，Perfect讨论了抗真菌药物的开发，包括当前使用的药物类别，新型分子靶标，可以从其他领域重新利用的药物以及免疫指导疗法的使用等方面的进展。