Scaffold Diversity from N-Acyliminium Ions,Chemical Reviews

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Scaffold Diversity from N-Acyliminium Ions
Chemical Reviews ( IF 51.4 ) Pub Date : 2017-05-11 00:00:00 , DOI: 10.1021/acs.chemrev.6b00806
Peng Wu _{1,

2,

3,

4,

5} , Thomas E. Nielsen _{1,

2,

6}

Affiliation

N-Acyliminium ions are powerful reactive species for the formation of carbon–carbon and carbon–heteroatom bonds. Strategies relying on intramolecular reactions of N-acyliminium intermediates, also referred to as N-acyliminium ion cyclization reactions, have been employed for the construction of structurally diverse scaffolds, ranging from simple bicyclic skeletons to complex polycyclic systems and natural-product-like compounds. This review aims to provide an overview of cyclization reactions of N-acyliminium ions derived from various precursors for the assembly of structurally diverse scaffolds, covering the literature over the past 12 years (from 2004 to 2015).

中文翻译：

N-酰基亚胺离子的支架多样性

N-酰基亚胺离子是形成碳-碳和碳-杂原子键的强大反应物种。依赖于N-酰基酰亚胺中间体的分子内反应的策略，也称为N-酰基酰亚胺离子环化反应，已被用于构建结构多样的支架，从简单的双环骨架到复杂的多环体系和类似天然产物的化合物。这篇综述旨在概述衍生自各种用于结构多样支架组装的各种前体的N-酰基亚胺离子的环化反应，涵盖了过去12年（从2004年至2015年）的文献。

更新日期：2017-05-11

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