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How the flagellum knows when to stop
Science ( IF 56.9 ) Pub Date : 2017-04-13 , DOI: 10.1126/science.356.6334.149-r
Stella M. Hurtley

Size Control The bacterial flagellum is important in bacterial pathogenesis and biofilm formation. It is a rotary nanomotor that allows bacteria to propel themselves through liquids and across surfaces. Researchers interested in nanoscale robotics use the bacterial flagellum as a model for a machine that self-assembles on the nanoscale. Cohen et al. examined exactly how the flagellum precisely measures its shaft so that it spans, but does not extend beyond the edge of, the periplasm. The growing flagellum uses a mechanism by which it “senses” when it hits the outer membrane and stops growing. Changing the width of the periplasmic space by remodeling a particular lipid changed the length of the flagellar shaft. Science , this issue p. [197][1] [1]: /lookup/doi/10.1126/science.aam6512

中文翻译:

鞭毛如何知道何时停止

大小控制细菌鞭毛在细菌发病机制和生物膜形成中很重要。它是一种旋转式纳米马达,可以让细菌在液体中和表面上推动自己。对纳米级机器人感兴趣的研究人员使用细菌鞭毛作为在纳米级自组装的机器的模型。科恩等人。确切地检查了鞭毛如何精确测量其轴以使其跨越但不超出周质的边缘。不断增长的鞭毛使用一种机制,当它碰到外膜并停止生长时,它会通过这种机制“感知”。通过重塑特定脂质来改变周质空间的宽度会改变鞭毛轴的长度。科学,这个问题 p。[197][1][1]:/lookup/doi/10.1126/science.aam6512
更新日期:2017-04-13
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