Dengue Virus Dengue virus (DENV) causes a large number of asymptomatic infections, so surveillance captures only a fraction of cases. Salje et al. developed a method for identifying the number of transmission chains of DENV from sequence data and serology. They found that sequential transmission of DENV typically occurs between households in the same neighborhood. Within high-density urban localities, such as Bangkok, there are surprisingly few transmission chains. This results in epidemic spikes within a regional background of endemicity. Large urban settings may thus act as a source of diverse viruses that can be transported elsewhere. Science , this issue p. [1302][1] [1]: /lookup/doi/10.1126/science.aaj9384

中文翻译：

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估计登革热的传播链

登革热病毒 登革热病毒 (DENV) 会导致大量无症状感染，因此监测只能捕获一小部分病例。萨杰等人。开发了一种从序列数据和血清学中识别 DENV 传播链数量的方法。他们发现 DENV 的顺序传播通常发生在同一社区的家庭之间。在曼谷等高密度城市地区，传输链少得惊人。这导致在地方性流行的区域背景下流行病高峰。因此，大型城市环境可能是多种病毒的来源，这些病毒可以传播到其他地方。科学，这个问题 p。[1302][1][1]：/lookup/doi/10.1126/science.aaj9384