Cell Signaling Macrophages eliminate dead or dying cells and identify and destroy invading microbes. However, they also exhibit nonimmune functions in development and homeostasis. Eom and Parichy show that macrophages are essential for postembryonic remodeling during adult pigment stripe formation in zebrafish (see the Perspective by Guilliams). Pigment cells relay signal-containing vesicles via cellular projections from one class of cell to another. Without macrophages, this signal relay fails, and adult stripes are disorganized. Science , this issue p. [1317][1]; see also p. [1258][2] [1]: /lookup/doi/10.1126/science.aal2745 [2]: /lookup/doi/10.1126/science.aam9743

中文翻译：

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细胞投影设置色素模式

细胞信号巨噬细胞消除死亡或垂死的细胞，并识别和摧毁入侵的微生物。然而，它们在发育和体内平衡方面也表现出非免疫功能。Eom 和 Parichy 表明，巨噬细胞对于斑马鱼成年色素条纹形成过程中的胚胎后重塑至关重要（参见 Guilliams 的观点）。色素细胞通过从一类细胞到另一类细胞的细胞投射来传递含有信号的囊泡。如果没有巨噬细胞，这种信号传递就会失败，成年条纹就会变得杂乱无章。科学，这个问题 p。[1317][1]; 另见第。[1258][2][1]：/lookup/doi/10.1126/science.aal2745 [2]：/lookup/doi/10.1126/science.aam9743