An immune cell organizes pigment cells during zebrafish stripe development Macrophages were first identified in transparent starfish larvae (Astropecten pentacanthus) more than a century ago, so it is fitting that a new function for macrophages would again be discovered in transparent marine larvae, this time from zebra fish (Danio rerio). On page 1317 of this issue, Eom and Parichy (1) reveal a wholly unexpected tissue-specific function of macrophages—their cardinal role in long-distance communication between nonimmune cells. In doing so, macrophages choreograph the patterning of pigment cells that eventually form the stripes on zebrafish.

中文翻译：

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巨噬细胞，长途中间人

免疫细胞在斑马鱼条纹发育过程中组织色素细胞 一个多世纪前首次在透明海星幼虫（Astropecten pentacanthus）中发现巨噬细胞，因此在透明海洋幼虫中再次发现巨噬细胞的新功能是合适的，这一次来自斑马鱼 (Danio rerio)。在本期第 1317 页，Eom 和 Parichy (1) 揭示了巨噬细胞完全出乎意料的组织特异性功能——它们在非免疫细胞之间的长距离通信中的主要作用。在这样做时，巨噬细胞会编排色素细胞的图案，最终在斑马鱼上形成条纹。