Single-walled carbon nanotubes (SWCNTs) have been incorporated in many emerging applications in the biomedical field including chemical sensing, biological imaging, drug delivery, and photothermal therapy. To overcome inherent hydrophobicity and improve their biocompatibility, pristine SWCNTs are often coated with surfactants, polymers, DNA, proteins, or lipids. In this paper, we report the effect of polyunsaturated fatty acids (PUFAs) on SWCNT photoluminescence. A decrease in the SWCNT bandgap emission (E11) and a new red-shifted emission (E11-) were observed in the presence of PUFAs. We attribute the change in SWCNT photoluminescence to the formation of oxygen-containing defects by lipid hydroperoxides through photo-oxidation. The observed changes in near-infrared emission of SWCNTs are important for understanding the interaction between SWCNTs and lipid biocorona. Our results also indicate that photoexcited SWCNTs can catalyze lipid peroxidation similarly to lipoxygenases.

中文翻译：

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多不饱和脂肪酸处理的单壁碳纳米管缺陷诱导的近红外光致发光

单壁碳纳米管 (SWCNT) 已被纳入生物医学领域的许多新兴应用，包括化学传感、生物成像、药物输送和光热疗法。为了克服固有的疏水性并提高其生物相容性，原始单壁碳纳米管通常涂有表面活性剂、聚合物、DNA、蛋白质或脂质。在本文中，我们报告了多不饱和脂肪酸 (PUFA) 对 SWCNT 光致发光的影响。在存在 PUFA 的情况下，观察到 SWCNT 带隙发射 (E11) 和新的红移发射 (E11-) 的减少。我们将 SWCNT 光致发光的变化归因于脂质氢过氧化物通过光氧化形成含氧缺陷。观察到的单壁碳纳米管近红外发射的变化对于理解单壁碳纳米管和脂质生物冠之间的相互作用很重要。我们的结果还表明，光激发的 SWCNT 可以像脂氧合酶一样催化脂质过氧化。