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Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates
Nature Materials ( IF 37.2 ) Pub Date : 2017-03-20 00:00:00 , DOI: 10.1038/nmat4866
Joshua C. Doloff , Omid Veiseh , Arturo J. Vegas , Hok Hei Tam , Shady Farah , Minglin Ma , Jie Li , Andrew Bader , Alan Chiu , Atieh Sadraei , Stephanie Aresta-Dasilva , Marissa Griffin , Siddharth Jhunjhunwala , Matthew Webber , Sean Siebert , Katherine Tang , Michael Chen , Erin Langan , Nimit Dholokia , Raj Thakrar , Meirigeng Qi , Jose Oberholzer , Dale L. Greiner , Robert Langer , Daniel G. Anderson

By studying the immune responses of animals to different types of biomaterial implants, colony stimulating factor-1 receptor is revealed as an important mediator of the foreign body reaction and a possible target for fibrosis inhibition.

中文翻译:

集落刺激因子-1受体是异物对啮齿动物和非人类灵长类动物中生物材料植入物反应的重要组成部分

通过研究动物对不同类型生物材料植入物的免疫反应,发现集落刺激因子-1受体是异物反应的重要介质,也是抑制纤维化的可能靶标。
更新日期:2017-04-11
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