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Real-time visualization of perforin nanopore assembly
Nature Nanotechnology ( IF 38.1 ) Pub Date : 2017-02-06 00:00:00 , DOI: 10.1038/nnano.2016.303
Carl Leung 1, 2 , Adrian W Hodel 1, 3 , Amelia J Brennan 4 , Natalya Lukoyanova 2 , Sharon Tran 4 , Colin M House 5 , Stephanie C Kondos 6 , James C Whisstock 6, 7 , Michelle A Dunstone 6, 7, 8 , Joseph A Trapani 5, 9 , Ilia Voskoboinik 4, 9 , Helen R Saibil 2 , Bart W Hoogenboom 1, 3, 10
Affiliation  

Perforin monomers self-assemble into pre-pores that first insert into the membrane and then recruit additional subunits to grow in size.

中文翻译:

穿孔素纳米孔组装的实时可视化

穿孔素单体自组装成预孔,首先插入膜中,然后招募额外的亚基以增大尺寸。
更新日期:2017-02-08
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