23. Fu, W.†; Liu, Z.†; Yang, Y.* Metalloenzyme-Catalyzed Radical Reactions Unknown or Uncommon in Native Enzymology. Chem. Rev. Submitted. (Invited contribution)

 

22. Fu, W.; Yang, Y.* Triplet Quenchers for Energy-transfer Photobiocatalysis. Nat. Catal. 2025, 8 (11), 1131–1132. https://doi.org/10.1038/s41929-025-01443-1 (Invited News & Views)

 

21. Fu, W.; Murcek, K.; Chen, J.; Liu, A.; Zhao, Y.; Liu, P.*; Yang, Y.* Catalytic Enantioselective Smiles Rearrangement Enabled by the Directed Evolution of P450 Radical Aryl Migratases. J. Am. Chem. Soc. 2025, 147 (14), 12197–12205.  https://doi.org/10.1021/jacs.5c01179

 

20. Fu, W.†; Liu, A.†; Yang, Y*. Diastereo- and Enantioselective Chemoenzymatic Synthesis of Chiral Tricyclic Intermediate of Anti-HIV Drug Lenacapavir. ACS Catalysis, 2025, 15 (3), 2045–2052. https://doi.org/10.1021/acscatal.4c07464. (Contributed equally)

Preprint from ChemRxiv is available: https://chemrxiv.org/engage/chemrxiv/article-details/6787c4ec6dde43c908adc15c

 

19. Fu, W.; Fu, Y.†; Zhao, Y.†; Wang, H.; Liu, P.*; Yang, Y.* A Metalloenzyme Platform for Catalytic Asymmetric Radical Dearomatization. Nat. Chem. 2024, 16 (12), 1999–2008. https://doi.org/10.1038/s41557-024-01608-8.

• Highlighted by Benjamin List and Lennart J. Brücher in Synfacts 2024, 20, 1193, “Enzymatic Asymmetric Radical Dearomatization of Electron-Rich Arenes Towards Chiral Spirocycles”
• Highlighted by X-MOL: https://www.x-mol.com/news/898194
• Highlighted by 南海CSG: https://mp.weixin.qq.com/s/cLU0UU4vKv_XAHcOcNo4gA
• Highlighted by 化学深耕堂：https://mp.weixin.qq.com/s/e436184_WP0qiH-sNKQWhA
• Highlighted by Biosyn世纪：https://mp.weixin.qq.com/s/ycILgjb0X3qVfGOGXDqQTg

 

18. Fu, W.; Neris, N. M.; Fu, Y.; Zhao, Y.; Krohn-Hansen, B.; Liu, P.*; Yang, Y.* Enzyme-Controlled Stereoselective Radical Cyclisation to Arenes Enabled by Metalloredox Biocatalysis. Nat. Catal. 2023, 6 (7), 628–636. https://doi.org/10.1038/s41929-023-00986-5. 

• Featured on the cover of Nature Catalysis (July 2023 issue).

• Highlighted by Paul Richardson in Synfacts 2024, 20, 0012, “Enzyme-Catalyzed Synthesis of Chiral 3,3-Disubstituted Oxindoles”
• Highlighted by UCSB’s The Current: Sonia Hernandez, “A ‘toolbox of biocatalysts’ improves control over free radicals”
• Highlighted by X-MOL: https://www.x-mol.com/news/860971
• Highlighted by 遇见生物合成：https://mp.weixin.qq.com/s/kFRwtr1PEBTN4Zfw-M2Scw

 

17. Chen, H.†; Fu, W.†; Yang, Y.* P450-Catalyzed Atom Transfer Radical Cyclization. In Methods in Enzymology; Academic Press, 2023. https://doi.org/10.1016/bs.mie.2023.09.007. (Contributed equally) (Invited contribution to the “P450 enzyme” issue).

 

16. Fu, W.; Yang, Y.* Undirected Biocatalytic Amination of Unactivated C(sp³)−H Bonds. Chem. Catal. 2022, 2 (12), 3287–3289. https://doi.org/10.1016/j.checat.2022.11.013. (Invited Preview)

 

15. Fu, W.; Tang, W.* Chiral Monophosphorus Ligands for Asymmetric Catalytic Reactions. ACS Catal. 2016, 6 (8), 4814–4858. https://doi.org/10.1021/acscatal.6b01001. (Review)

 

14. Fu, W.; Nie, M.; Wang, A.; Cao, Z.; Tang, W.* Highly Enantioselective Nickel-Catalyzed Intramolecular Reductive Cyclization of Alkynones. Angew. Chem. Int. Ed. 2015, 54 (8), 2520–2524. https://doi.org/10.1002/anie.201410700. 

 

13. Fu, W.; Wu, D.; Zhang, Z.; Huang, L.; Niu, Y.* C–C Oxidative Coupling Reaction of Ethylene-Bridged Azoles via Double C–H Activation With the Catalyst CuX (X = I, Br). Synth. React. Inorg. Met.-Org. Nano-Met. Chem. 2012, 42 (6), 878–881. https://doi.org/10.1080/15533174.2011.652273.

 

12. Fu, W.; Wang, H.; Wang, B.; Duan, H.; Cui, X.; Wang, W.; Wang, Z.; Zhang, Z.; Liu, X.; Niu, Y.* Syntheses and Crystal Structures of Four Supramolecular Halides/Pseudohalides: [(ZnCl4)(BPX)], [(CdCl4)(BPX)], [(HgCl4)(BPX)], and [Cu4(SCN)6(BPX)]n Directed by 1,4-Bis(Pyridinium)Xylol Cations. Synth. React. Inorg. Met.-Org. Nano-Met. Chem. 2011, 41 (3), 272–278. https://doi.org/10.1080/15533174.2011.555859. 

 

11. Liu, G.; Fu, W.; Mu, X.; Wu, T.; Nie, M.; Li, K.; Xu, X.; Tang, W.* Pyrrolidines and Piperidines Bearing Chiral Tertiary Alcohols by Nickel-Catalyzed Enantioselective Reductive Cyclization of N-Alkynones. Commun. Chem. 2018, 1 (1), 90. https://doi.org/10.1038/s42004-018-0092-1.

 

10. Fu, Y.; Chen, H.; Fu, W.; Garcia-Borràs, M.; Yang, Y.*; Liu, P.* Engineered P450 Atom-Transfer Radical Cyclases Are Bifunctional Biocatalysts: Reaction Mechanism and Origin of Enantioselectivity. J. Am. Chem. Soc. 2022, 144 (29), 13344–13355. https://doi.org/10.1021/jacs.2c04937.

 

9. Chen, Y.; Zhu, Y.; Yue, P.; Verma, N.; Brotherton-Pleiss, C.; Fu, W.; Nakamura, K.; Chen, W.; Murali, R.; Tius, M.; Lopez-Tapia, F.*; Turkson, J.* Azetidine Ring, Salicylic Acid, and Salicylic Acid Bioisosteres as Determinants of the Binding Characteristics of Novel Potent Compounds to Stat3. Bioorg. Med. Chem. Lett. 2024, 97, 129565. https://doi.org/10.1016/j.bmcl.2023.129565.

 

8. Yue, P.; Zhu, Y.; Brotherton-Pleiss, C.; Fu, W.; Verma, N.; Chen, J.; Nakamura, K.; Chen, W.; Chen, Y.; Alonso-Valenteen, F.; Mikhael, S.; Medina-Kauwe, L.; Kershaw, K. M.; Celeridad, M.; Pan, S.; Limpert, A. S.; Sheffler, D. J.; Cosford, N. D. P.; Shiao, S. L.; Tius, M. A.; Lopez-Tapia, F.*; Turkson, J.* Novel Potent Azetidine-Based Compounds Irreversibly Inhibit Stat3 Activation and Induce Antitumor Response against Human Breast Tumor Growth in Vivo. Cancer Lett. 2022, 534, 215613. https://doi.org/10.1016/j.canlet.2022.215613.

 

7. Brotherton-Pleiss, C.#; Yue, P.#; Zhu, Y.; Nakamura, K.; Chen, W.; Fu, W.; Kubota, C.; Chen, J.; Alonso-Valenteen, F.; Mikhael, S.; Medina-Kauwe, L.; Tius, M. A.; Lopez-Tapia, F.; Turkson, J.* Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors. J. Med. Chem. 2021, 64 (1), 695–710. https://doi.org/10.1021/acs.jmedchem.0c01705.

 

6. Nie, M.; Fu, W.; Cao, Z.; Tang, W.* Enantioselective Nickel-Catalyzed Alkylative Alkyne–Aldehyde Cross-Couplings. Org. Chem. Front. 2015, 2 (10), 1322–1325. https://doi.org/10.1039/C5QO00148J.

 

5. Xu, G.; Fu, W.; Liu, G.; Senanayake, C. H.; Tang, W.* Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions. J. Am. Chem. Soc. 2014, 136 (2), 570–573. https://doi.org/10.1021/ja409669r.

 

4. Mu, Y.; Zhang, T.; Cheng, Y.; Fu, W.; Wei, Z.; Chen, W.; Liu, G.* Efficient Synthesis of Tetrahydrofurans with Chiral Tertiary Allylic Alcohols Catalyzed by Ni/ P -Chiral Ligand DI-BIDIME. Catal. Sci. Technol. 2021, 11 (6), 2306–2315. https://doi.org/10.1039/D0CY02470H.

 

3. Du, H.; Fu, W.; Zhang, S.; Li, L.; Wang, H.; Yue, Z.; Zhang, W.; Niu, Y.*; Zhu, Y. Six Cation-Templated Halometal Complexes and C–H Activation of Alkylene-Bridged Azoles. J. Coord. Chem. 2014, 67 (5), 807–821. https://doi.org/10.1080/00958972.2014.908288.

 

2. Qiao, Y.; Fu, W.; Yue, J.; Liu, X.; Niu, Y.*; Hou, H.* Role of Cooperative Templates in the Self-Assembly Process of Microporous Structures: Syntheses and Characterization of 12 New Silver Halide/Thiocyanate Supramolecular Polymers. CrystEngComm 2012, 14 (9), 3241–3249. https://doi.org/10.1039/C2CE06687D.

 

1. Yue, J.; Wang, W.; Fu, W.; Han, X.; Zhang, Z.; Wang, L.; Niu, Y.* Syntheses, Crystal Structures, and Fluorescent Properties of Two Cation-Induced Complexes: [(CdI4)(BPHX)] and [(Ag2I4)(BPHX)]. Synth. React. Inorg. Met.-Org. Nano-Met. Chem. 2011, 41 (1), 100–106. https://doi.org/10.1080/15533174.2010.538020.