2024级博士研究生
本科毕业于徐州医科大学,硕士毕业于上海交通大学
研究方向:针对STING通路的纳米免疫调控
发表论文:
Chen, H.†; Qu, H.† *; Pan, Y.; Cheng, W.; Xue, X*. Manganese-coordinated nanoparticle with high drug-loading capacity and synergistic photo-/immuno-therapy for cancer treatments. Biomaterials, 2025, 312, 122745. IF=12.8
Chen, H.; Qu, H.; Lu, B.; Pan, Y.; Yang, J.; Duan, Z.; Wu, J.; Wang, Y.; Wang, C.; Hu, R.*; Xue, X.*, A metal-coordination stabilized small-molecule nanomedicine with high drug-loading capacity and synergistic photochemotherapy for cancer treatment. Nanoscale 2024, 16, 14734-14747. IF=5.8. Selected as "Nanoscale 2024 HOT article" and "Nanoscale 2024 Emerging Investigators (新锐科学家)"
Qu, H.†; Chen, H.†; Cheng, W.; Pan, Y.; Duan, Z.; Wang, Y.; Liang, X-J.*; Xue, X.* Charge-Reversible Crosslinked Nanoparticle for Improved Pro-Apoptotic Peptide Delivery and Synergistic Photodynamic Cancer Therapy. Nano Research, 2023 16 (12): 13267-13282. IF=10.269
Chen H, Wang Y, Gao Z, Yang W, Gao J. Assessing the performance of three resveratrol in binding with SIRT1 by molecular dynamics simulation and MM/GBSA methods: the weakest binding of resveratrol 3 to SIRT1 triggers a possibility of dissociation from its binding site. J Comput Aided Mol Des. 2019;33(4):437‐446. doi:10.1007/s10822-019-00193-0.
Gao J, Zhang Y, Chen H, et al. Computational insights into the interaction mechanism of transcription cofactor vestigial-like protein 4 binding to TEA domain transcription factor 4 by molecular dynamics simulation and molecular mechanics generalized Born/surface area) calculation. J Biomol Struct Dyn. 2019;37(10):2538‐2545. doi:10.1080/07391102.2018.1491889.
Chen, H.; Timashev, P.; Zhang, Y.; Xue, X.*; Liang, X.-J.*, Nanotechnology-based combinatorial phototherapy for enhanced cancer treatment. RSC Advances 2022, 12 (16), 9725-9737.