Fenselau, Catherine - University of Maryland - Department of Chemistry & Biochemistry

个人简介

A.B. Chemistry 1961, Bryn Mawr College, Bryn Mawr, PA Ph.D. Organic Chemistry 1965, Stanford University (with Carl Djerassi) Postdoctoral Fellow 1966, Univ. Calif. Berkeley, (with Melvin Calvin) (AAUW Fellowship) Postdoctoral Fellow 1967, NASA Space Sciences Laboratory (with Melvin Calvin and A.L. Burlingame)

研究领域

Mechanisms of tumor resistance to chemotherapy and immunotherapy; new methods for proteomics; exosomes and their proteomes and analysis of polyubiquitins

近期论文

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Burke, M., Oei, M., Edwards, N., Ostrand-Rosenberg, S. and Fenselau, C. Ubiquitinated Proteins in Exosomes Secreted by Myeloid-derived Suppressor Cells. Journal of Proteome Research DOI 10.1021/pr500854x (2014). Lee, A.E., Castaneda, C., Wang, Y., Fushman, D. and Fenselau, C. Preparing to Read the Ubiquitin Code: A Middle-Out Strategy for Characterization of all Lysine-Linked Diubiquitins. Journal of Mass Spectrometry DOI 10.1002/jms.3458 (2014). Geis-Asteggiante, L., Dhabaria, A., Edwards, N., Ostrand-Rosenberg, S. and Fenselau, C. Top-down analysis of low mass proteins in exosomes shed by murine myeloid-derived suppressor cells. International Journal of Mass Spectrometry DOI: 10.1016/j.ijms.2014.08.035 (2014). Kim, S., Rose, R., Choksawangkarn, W., Graham, L., Hu, J., Fenselau, C. and Lee, S.B. Comparison of Nanowire Pellicles for Plasma Membrane Enrichment: Coating Nanowires on Cell. J. Nanopart. Res. 15: 2133-2140 (2013). DOI 10.1007/s11051-013-2133-0 Burke, M., Choksawangkarn, W., Edwards, N., Ostrand-Rosenberg, S. and Fenselau, C. Exosomes from myeloid derived suppressor cells carry biologically active proteins. J. Prot. Research 13, 836−843 (2014) DOI 10.1021/pr400879c. Choksawangkarn, W., Kim, S., Cannon, J., Edwards, N., Lee, S.B. and Fenselau, C. Enrichment of plasma membrane proteins using nanoparticle pellicles: comparison between silica and higher density nanoparticles. J. Proteome Res. 12: 1134-1141 (2013). Cannon, J., Nakasone, M., Fushman, D. and Fenselau, C. Proteomic Identification and Analysis of K63-linked Ubiquitin Conjugates. Anal. Chem. 84: 10121-10128 (2012).