个人简介

Ph.D., Rutgers-The State University of New Jersey (1989); M.S. University of Wisconsin (1985); B.S. Louisiana State University (1982)

研究领域

Analytical/Biochemistry & Chemical Biology/Materials/Polymers & Nanoscience

Scanning Force Microscopy, Biological Chemistry

近期论文

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Lamour, V., Hogan, B. P., Erie, D. A. & Darst, S. A. (2006). Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage. J Mol Biol 356, 179-88. Brenowitz, M., Erie, D. A. & Chance, M. R. (2005). Catching RNA polymerase in the act of binding: intermediates in transcription illuminated by synchrotron footprinting. Proc Natl Acad Sci U S A 102, 4659-60. Tessmer, I., Moore, T., Lloyd, R. G., Wilson, A., Erie, D. A., Allen, S. & Tendler, S. J. (2005). AFM studies on the role of the protein RdgC in bacterial DNA recombination. J Mol Biol 350, 254-62. Kunkel, T. A. & Erie, D. A. (2005). DNA mismatch repair. Annu Rev Biochem 74, 681-710. Yang, Y., Sass, L. E., Du, C., Hsieh, P. & Erie, D. A. (2005). Determination of protein-DNA binding constants and specificities from statistical analyses of single molecules: MutS-DNA interactions. Nucleic Acids Res 33, 4322-34. Guthold, M., Liu, W., Stephens, B., Lord, S. T., Hantgan, R. R., Erie, D. A., Taylor, R. M., Jr. & Superfine, R. (2004). Visualization and mechanical manipulations of individual fibrin fibers suggest that fiber cross section has fractal dimension 1.3. Biophys J 87, 4226-36. Bao, K. K., Wang, H., Miller, J. K., Erie, D. A., Skalka, A. M. & Wong, I. (2003). Functional oligomeric state of avian sarcoma virus integrase. J Biol Chem 278, 1323-7. Yang, Y., Wang, H. & Erie, D. A. (2003). Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopy. Methods 29, 175-87. Holmes, S. F. & Erie, D. A. (2003). Downstream DNA sequence effects on transcription elongation. Allosteric binding of nucleoside triphosphates facilitates translocation via a ratchet motion. J Biol Chem 278, 35597-608. Wang, H., Yang, Y., Schofield, M. J., Du, C., Fridman, Y., Lee, S. D., Larson, E. D., Drummond, J. T., Alani, E., Hsieh, P. & Erie, D. A. (2003). DNA bending and unbending by MutS govern mismatch recognition and specificity. Proc Natl Acad Sci U S A 100, 14822-7. Holmes, S. F., Foster, J. E. & Erie, D. A. (2003). Kinetics of multisubunit RNA polymerases: experimental methods and data analysis. Methods Enzymol 371, 71-81. Hogan, B. P., Hartsch, T. & Erie, D. A. (2002). Transcript cleavage by Thermus thermophilus RNA polymerase. Effects of GreA and anti-GreA factors. J Biol Chem 277, 967-75. Xue, Y., Ratcliff, G. C., Wang, H., Davis-Searles, P. R., Gray, M. D., Erie, D. A. & Redinbo, M. R. (2002). A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'- 5' exonuclease and 5'-protruding strand endonuclease activities. Biochemistry 41, 2901-12. Erie, D. A. (2002). The many conformational states of RNA polymerase elongation complexes and their roles in the regulation of transcription. Biochim Biophys Acta 1577, 224-39. Drotschmann, K., Hall, M. C., Shcherbakova, P. V., Wang, H., Erie, D. A., Brownewell, F. R., Kool, E. T. & Kunkel, T. A. (2002). DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers. Biol Chem 383, 969-75. Davis-Searles, P. R., Saunders, A. J., Erie, D. A., Winzor, D. J. & Pielak, G. J. (2001). Interpreting the effects of small uncharged solutes on protein-folding equilibria. Annu Rev Biophys Biomol Struct 30, 271-306. /p> Ratcliff, G. C. & Erie, D. A. (2001). A novel single-molecule study to determine protein--protein association constants. J Am Chem Soc 123, 5632-5. Foster, J. E., Holmes, S. F. & Erie, D. A. (2001). Allosteric binding of nucleoside triphosphates to RNA polymerase regulates transcription elongation. Cell 106, 243-52. Hall, M. C., Wang, H., Erie, D. A. & Kunkel, T. A. (2001). High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer. J Mol Biol 312, 637-47. /p> Guthold, M. & Erie, D. A. (2001). Single-molecule study reveals a complex E. coli RNA polymerase. Chembiochem 2, 167-70. Guthold, M.; Falvo, M. R.; Matthews, W. G.; Paulson, S.; Washburn, S.; Erie, D. A.; Superfine, R.; Brooks, F. P.; Taylor, R. M. "Controlled manipulation of molecular samples with the nanoManipulator"; IEEE-ASME Trans. Mechatron. 2000, 5, 189-198. Saunders, A. J., Davis-Searles, P. R., Allen, D. L., Pielak, G. J. & Erie, D. A. (2000). Osmolyte-induced changes in protein conformational equilibria. Biopolymers 53, 293-307. Superfine, R.; Falvo, M.; Steele, J.; Matthews, G.; Guthold, M.; Erie, D.; Helser, A.; Jones, M. G.; Taylor, R. M.; Washburn, S. In Microbeam Analysis 2000, Proceedings; IOP PUBLISHING LTD: Bristol, 2000, pp 369-370. Wong, O. K.; Guthold, M.; Erie, D.; Gelles, J. "Multiple conformations of lactose repressor-DNA looped complexes revealed by single molecule techniques"; Faseb J. 2000, 14, 766. Xue, Y., Hogan, B. P. & Erie, D. A. (2000). Purification and initial characterization of RNA polymerase from Thermus thermophilus strain HB8. Biochemistry 39, 14356-62.