沈悦海 - 昆明理工大学 - 生命科学与技术学院

个人简介

教育经历： 1. 1999，中国科学院上海有机化学研究所，有机化学专业，博士 2. 1996，厦门大学，有机化学专业，硕士 3. 1993，厦门大学，化学专业，学士工作经历： 1. 2010至今，昆明理工大学，生命科学与技术学院，教授 2. 2008 - 2010，美国Anichem化学公司，高级研究员 3. 2002 - 2008，美国密歇根州立大学，生理系，博士后 4. 2000 - 2002，美国佛蒙特大学，化学系，博士后 5. 1999 - 2000，日本东北大学，理学院，博士后

研究领域

主要从事有机合成方法、金属有机化学和药物化学研究。围绕重大社会关切，发展高效绿色的合成策略，同时开展新机制药物和活性天然产物合成研究。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Kai Tan, Huan Yan, Pengbo Lu, Yuehui Liu, Ruigeng Ji, Zhongxian Liu, Ya-Min Li, Fu-Chao Yu, Yuehai Shen*. Access to multi-substituted 2(5H)-furanones using hydrogen bonding-promoted ring-closing metathesis and polyamine workup. J. Org. Chem. 2019, accepted. 2. 颜廷斌, 刘跃辉, 沈悦海*. 钌催化烯烃复分解反应中的氢键效应. 有机化学, 2018, 38, 2491-2500. 3. 潘陈玲, 孟浩, 汪亮亮, 沈悦海*, 左之利*, 王冠林, 张宽仁. 阿片类药物研发近期热点. 有机化学, 2018, 38, 2625-2632. 4. Shoupu Yi, Qinghong Kong, Yulei Li, Chenling Pan, Jie Yu, Benqiang Cui, Yingfei Wang, Guanlin Wang, Peilan Zhou, Lili Wang, Zehui Gong, Ruibin Su, Yuehai Shen*, Gang Yu*, Kwen-Jen Chang*. Opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability. Acta Pharmacol. Sin. 2017, 38 (7), 977-989. 5. Liang Feng, Yuehui Liu, Bo Hou, Zaifeng Yuan, Fu-Chao Yu, Tingbin Yan, Qi Qin, Ruigeng Ji, Ya-Min Li, Yuehai Shen*, Zhi-Li Zuo*. Hydrogen bonding-promoted efficient Ru-catalyzed ring-closing metathesis of demanding homoallyl 2-(hydroxymethyl)acrylates. Org. Biomol. Chem. 2016, 14, 10705-10713. 6. Benqiang Cui, Jie Yu, Fu-Chao Yu, Ya-Min Li, Kwen-Jen Chang, Yuehai Shen*. Synthesis of (1R,4R)-2,5-diazabicyclo[2.2.1]heptane derivatives by an epimerization-lactamization cascade reaction. RSC Adv. 2015, 5, 10386-10392. 7. Xuge Liu, Zhilin Yang, Yamin Li, Fan Yang, Liang Feng, Nengzhong Wang, Debiao Ma, Kwen-Jen Chang, Yuehai Shen*. A practical nickel-catalyzed reductive alkylation of amidophenyl bromides. Tetrahedron 2014, 70, 9522-9529. 8. Fan Yang, Liang Feng, Nengzhong Wang, Xuge Liu, Jun Li, Yuehai Shen*. Practical synthesis of C1-8 fragment of autolytimycin via a chelation-controlled diastereoselective addition of diisopropenylzinc to a-methoxy aldehyde. Tetrahedron 2013, 69, 9463-9468. 9. Yuehai Shen, Qian Xie, Monica Norberg, Edward Sausville, George F. Vande Woude, David Wenkert*. Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasmin activation. Bioorg. Med. Chem. 2005, 13, 4960-4971. 10. Gregory K. Friestad*, Yuehai Shen, Erik L. Ruggles. Enantioselective radical addition to N-acylhydrazones mediated by chiral Lewis acids. Angew. Chem. Int. Ed. 2003, 42, 5061-5063. 11. Yuehai Shen, Gregory K. Friestad*. Comparison of electrophilic amination reagents for N-amination of 2-oxazolidinones and application to synthesis of chiral hydrazones. J. Org. Chem. 2002, 67, 6236-6239.