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个人简介

教育背景 2007.9-2010.6 北京化工大学 生命学院,博士 (化学工程与技术专业) 2004.9-2007.6 北京化工大学 生命学院,硕士 (制药工程专业) 2000.9-2004.6 北京化工大学 化工学院,学士(生物工程专业) 工作经历 2010.7-2012.6 北京化工大学理学院,博士后 2014.1-2015.1 Georgia Institute of Technology 化学系,访问学者 2012.7-至今 北京化工大学生命科学与技术学院,副教授

研究领域

主要从事新药的设计合成,新药研发以及超分子自组装体的设计及应用等化学生物学方面的研究工作

近期论文

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Mengyao Zhu, Hang Zhou, Dandan Ji, Gang Li, Fang Wang, Dingyun Song, Bo Deng, Chao Li, Renzhong Qiao. A near-infrared fluorescence probe for ultrafast and selective detection of peroxynitrite with large Stokes shift in inflamed mouse models. Dyes and Pigments, 2019, 168, 77-83. Top Yilan Ju, Jintao Wu, Xi Yuan, Luqing Zhao, Ganlin Zhang, Chao Li, and Renzhong Qiao. Design and Evaluation of Potent EGFR Inhibitors through the Incorporation of Macrocyclic Polyamine Moieties into the 4‑Anilinoquinazoline Scaffold. J. Med. Chem. 2018, 61 (24), 11372-11383. Top 封面文章 G. Li, D. D. Ji, S. M. Zhang, J. M. Li, C. Li*, R. Z. Qiao*. A mitochondria-targeting fluorescence turn-on probe forhypochlorite and its applications for in vivo imaging. Sens. Actuators, B. 2017, 252, 127-133. Top D. D. Ji, G. Li, S. M. Zhang, M. Y. Zhu, C. Li*, R. Z. Qiao*. Mitochondria-targeted fluorescence probe for endogenoushypochlorite imaging in living cells and zebrafishs. Sens. Actuators, B. 2018, 259, 816-824. Top H. Zhou, J. H. Gao, Z. H. Chen, S. Duan, C. Li*, R. Z. Qiao*. Double-strand cleavage of DNA by a polyamide-phenazine-di-N-oxide conjugate. Bioorg. Med. Chem. Lett. 2018, 28, 284-288. C. Li, B. J. Cafferty, S. C. Karunakaran, G. B. Schuster, N. V. Hud. Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: implications for the possible origins of RNA. Phys. Chem. Chem. Phys., 2016, 18, 20091-20096. Top 封面文章 Zhang J, Zhao B, Li C, Zhu X, Qiao R*. A BODIPY-based "turn-on" fluorescent and colorimetric sensor for selective detection of Cu2+ in aqueous media and its application in cell imaging. Sens. Actuators, B. 2014, 196, 117-122. Top H. Zhou, D. Chen, J. K. Bai, X. L. Sun, C. Li*, R. Z. Qiao*. Effect of ligand sequence-specific modification on DNA hybrid catalysis. Org. Biomol. Chem. 2017, 15, 6738-6745. 封面文章 J. K. Bai, H. Zhou, X. L. Sun, D. Chen, C. Li, R. Z. Qiao. Insight into Stereo-Induction by Minor Modification in the Ligand in DNA-Based Hybrid Catalysis. Catal. Lett. 2018, 148 (11), 3315-3324. H. CHEN, H. ZHOU, S. WANG, G. LI, J. ZHANG F. WANG, C. LI, R. Z. QIAO. An isolated method and assignment for critical impurities in semi-synthetic process of arbekacin sulfate. Pharmazie, 2019, 74, 352-356. Chunying Ma, Xiao Zhang, Changguo Du, Baojing Zhao, Chunhua He, Chao Li*, and Renzhong Qiao. Water-soluble Cationic Polyphosphazenes Grafted with Cyclic Polyamine and Imidazole as An Effective Gene Delivery Vector. Bioconjugate Chem. 2016, 27, 1005-1012. Ma C, Zhang J, Guo L, Du C, Song P, Zhao B, Li L, LI C*, Qiao R, Cyclen Grafted with poly[(Aspartic acid)-co-Lysine]: Preparation, Assembly with Plasmid DNA, and in Vitro Transfection Studies. Mol. Pharmaceutics 2016, 13, 47-54. Top Qiao H, Ma C, Zhang X, Jing X, LI C*, Zhao Y. Insight into DNA Minor Groove Unspecific Binding of Pyrrole Polyamide. Bioconjugate Chem. 2015, 26, 2054-2061. Du C, Li L, Wang H, Zhang J, Yang X, Li C*, Qiao R*, Hepatocyte targeting and sustained release activity of water-soluble anti-HBV prodrug: Lactobionic acid grafted chitosan–lamivudine conjugate. React. Funct. Polym. 2016, 98, 48-55. Li L, Zhao F, Zhao B, Zhang J, Li C*, Qiao R*, Chitosan Grafted with Phosphorylcholine and Macrocyclic Polyamine as An Effective Gene Delivery Vector: Preparation, Characterization and In Vitro Transfection. Macromol. Biosci. 2015, 15, 912-916 Ma C, Chen H, Li C*, Zhang J, Qiao R*. IDB-containing low molecular weight short peptide as efficient DNA cleavage reagent. Org. Biomol. Chem. 2015, 13, 4524-4531. Li L, Zhang J, Li C, Chen L, Qiao R*. A facile method for synthesizing water-soluble and superior sustained release anti-HIV prodrug SCs-d4T. Mater. Sci. Eng., C. 2015, 49, 84-92. Zhang Y, He H, Zhang J, Liu F, Li C, Wang B, Qiao R*, HPLC-ELSD determination of kanamycin B in the presence of kanamycin A in fermentation broth. Biomed. Chromatogr. 2015, 29(3), 396-401. Ma C, Li C, Luan X, Zhang J, Qiao R*, Zhao Y. Electrospray ionization mass spectrometric studies on the characteristic fragmentation of Asp/cyclen conjugates. Rapid Commun. Mass Spectrom. 2014, 28(6), 645-652. Li C, Ma C, Zhang J, Qian N, Ding J, Qiao R*, Zhao Y. Design and synthesis of novel distamycin-modified nucleoside analogues as HIV-1 reverse transcriptase inhibitors. Antiviral Res. 2014, 102, 54-60.

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