朱冬青 - 武汉大学

个人简介

学习简历 1998.9―2002.8 山东大学攻读生物技术专业学士学位 2002.9―2008.8 上海交通大学攻读微生物学专业博士学位工作简历 2008.9―2011.8 布朗大学化学系 Post doctoral research associate 2011.9― 武汉大学药学院副教授

研究领域

天然产物生物合成的分子遗传学、生物化学及组合生物合成

近期论文

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1. Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L, Deng Z. Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis. Appl Microbiol Biotechnol. 2011 Oct;92(2):337-45. 2. Zhu D*, Seo MJ*, Ikeda H, Cane DE. Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.（*, co-first author） J Am Chem Soc. 2011 Feb 23;133(7):2128-31. 3. Seo MJ*, Zhu D*, Endo S, Ikeda H, Cane DE. Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.（*, co-first author） Biochemistry. 2011 Mar 15;50(10):1739-54. 4. Zhao C, Coughlin JM, Ju J, Zhu D, Wendt-Pienkowski E, Zhou X, Wang Z, Shen B, Deng Z. Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units. J Biol Chem. 2010 Jun 25;285(26):20097-108. 5. He Y, Zhu D, Bai L, Deng Z. Cloning of Antibiotic Biosynthetic Gene clusters from Genomic library by Narrow-down PCR. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY. 2009; 43(1):5-8. Chinese 6. Zhu D, He Y, Bai L, Deng Z. Positive Regulation of Avermectin Biosynthesis by AveR in Streptomyces avermitili. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY. 2008; 42(9):1448-1452. Chinese 7. Zhu D, He X, Zhou X, Deng Z. Expression of the melC operon in several Streptomyces strains is positively regulated by AdpA, an AraC family transcriptional regulator involved in morphological development in Streptomyces coelicolor. J Bacteriol. 2005 May;187(9):3180-7. 8. Zhang X, Zhu D, Wang D, Lin J, Qu Y, Yu S. [Study on xylose fermentation by Neurospora crassa].Wei Sheng Wu Xue Bao. 2003 Aug;43(4):466-72. Chinese. 9. Zhang X, Zhu D, Wang D, Lin J, Qu Y, Yu S. [Production and Some Properties of Xylanase from Neurospora crassa]. JOURNAL OF CELLULOSE SCIENCE AND TECHNOLOGY . 2002; 10(04). Chinese