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个人简介

学习经历: 1988/09-1992/06,武汉大学病毒及分子生物学系,学士; 1996/09-1998/09,武汉大学生命科学学院,硕士; 1998/09-2002/06,武汉大学生命科学学院,博士。 主要工作经历与任职 2013/01-至今,武汉大学, “珞珈学者”特聘教授; 2007/12-至今,武汉大学医学部,教授; 2007/03-2007/12,武汉大学医学部,副教授; 2005/04-2007/03,美国Stanford大学医学院,博士后; 2005/12-2007/03,武汉大学生命科学学院,副教授; 2002/12-2005/12,武汉大学生命科学学院,讲师; 2001/07-2002/12,武汉大学生命科学学院,助教; 1992/07-1996/09,卫生部武汉生物制品研究所,实习研究员。

研究领域

研究方向是病毒致病机制研究以及相关疾病的诊断以及治疗研究,主要是研究病毒导致的神经精神疾病、肿瘤等多种疾病中的免疫病理损伤的分子机制,如病毒感染或相关病毒蛋白导致宿主细胞中TLR、Wnt、MAPK、ERK、Jak等等多种信号通路改变,探索相关疾病的早期诊断以及SiRNA治疗研究手段。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1) Lijuan Liu, Xiaobei Chen, Shuixiang Xie, Chuanjie Zhang, Zhenpeng Qiu, Fan Zhu(朱帆)(通讯作者)*. Variant 1 of KIAA0101, overexpressed in hepatocelluler carcinoma, prevents Doxorubicin-induced apoptosis by inhibiting p53 activation. HEPATOLOGY. 2012; 56 (5): 1760-9. (影响因子:12.003,SCI一区) (2) Honglian Yu , Tao Liu , Zhankui Zhao, Yatang Chen , Jie Zeng , Shaojun Liu, Fan Zhu(朱帆)(通讯作者)*. Mutations in 3' long terminal repeat of HERV-W family in chromosome 7 upregulate syncytin-1 expression in urothelial cell carcinoma of the bladder through interacting with c-Myb. Oncogene. 2014; 33(30): 3947-58. (影响因子:8.559,SCI一区) (3) Wenjie Huang, Shan Li, Yuanmin Hu, Hongnian Yu, Feng Luo, Qi Zhang, Fan Zhu*(通讯作者). Implication of the env Gene of the Human Endogenous Retrovirus W Family in the Expression of BDNF and DRD3 and Development of Recent-Onset Schizophrenia. Schizophr Bull. 2011; 37: 988-1000.(影响因子:8.8,SCI一区) (4) Wenjie Huang, Zhongchun Liu, Wei Wei, Gaohua Wang Jianguo Wu, Fan Zhu*(通讯作者). Human Endogenous Retroviral pol RNA and protein detected and identified in the blood of individuals with schizophrenia. Schizophrenia research, 2006; 83(2-3): 193-9.(影响因子: 4.264) (5) Wei Wei, Wenjie Huang, Yin Pan, Fan Zhu*(通讯作者), Jianguo WU. Functional switch of viral protein HBx on cell apoptosis, transformation, and tumorigenesis in association with oncoprotein. Cancer Letters. 2006; 244(1):119-28.(影响因子: 3.277) (6) Shan Li#, Zhongchun Liu#, Shijin Yin, Yatang Chen, Honglian Yu, Jie Zeng, Qi Zhang, Fan Zhu(朱帆)(通讯作者)*. Human endogenous retrovirus W family envelope gene activates the small conductance Ca2+-activated K+ channel in human neuroblastoma cells through CREB. Neuroscience . 2013; 247 : 164-74. (影响因子:3.327) (7) Zhenpeng Qiu, Benhong Zhou, Long Jin, Honglian Yu, Lijuan Liu, Youyi Liu, Chengchen Qin, Shuixiang Xie, Fan Zhu(朱帆)(通讯作者)*. In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells. Food Chem Toxicol . 2013; 59: 428-37. (影响因子:2.61,SCI二区) (8) Lijuan Liu, Shuixiang Xie, Chuanjie Zhang, Fan Zhu(朱帆)(通讯作者)*. Aberrant regulation of alternative pre-mRNA splicing in hepatocellular carcinoma. Crit Rev Eukaryot Gene Expr. 2014; 24(2): 133-49. (影响因子:2.385) (9) Honglian Yu, Zhankui Zhao, Fan Zhu(朱帆)(通讯作者)*. The role of human endogenous retrovirus long terminal repeat in human cancer. Int J Mol Med. 2013; 32(4): 755-62.(影响因子:1.88)

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