个人简介
教育背景:
1982.09 - 1986.07,华中农业大学,学士学位
1986.09 - 1989.07,中国科学院水生生物研究所,硕士学位
1999.09 - 2002.06,武汉大学,博士学位
2003.07 - 2004.01,中国科学院水生生物研究所,访问学者
2008.01 - 2009.01,夏威夷大学,访问学者
工作经历:
1989.07 - 1992.03,中科院武汉分院计算机技术开发公司,助理工程师
1992.03 - 1993.01,水利部、中科院水库渔业研究所,助理研究员
1993.01 - 1997.01,武汉大学基础医学院人体寄生虫学教研室,讲师
1997.01 - 2002.10,武汉大学基础医学院人体寄生虫学教研室,副教授
1997.01 - 2002.10,武汉大学基础医学院人体寄生虫学教研室,教授
2004.06 - 至今,武汉大学基础医学院人体寄生虫学教研室,教授、博导
2013.05 - 2021.10,武汉大学基础医学院人体寄生虫学教研室,主任
获奖荣誉:
1995 年,被评为湖北省优秀青年教师
1997 年,被评为卫生部防治地方病跨世纪优秀科技工作者
1998 年,被评为湖北省高等学校先进女职工
1999 年,荣获第四届湖北省青年科技奖
2000 年,获湖北省人民政府专项津贴
2001 年,获湖北省科技进步奖二等奖
2003 年,获第五批湖北省优秀博士论文奖
获省部级教学成果奖一等奖和 “全国优秀教育音像制品奖” 一等奖各 1 项
研究领域
血吸虫生物学及其与宿主的相互关系
主要聚焦于寄生虫生物学及其与宿主相互关系研究,目前主持国家自然科学基金2项,参加科技部重点研发计划“蓝色粮仓科技创新”专项1项,研究结果主要发表在《FASEB J》、《FRONT MICROBIOL》、《PARASITES & VECTORS》、《ACTA TROP》、《PARASITOL RES》等期刊上。
近期论文
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1. 汤宏斌,程腊英,熊涛, 董惠芬*,蒋明森。细菌脂多糖诱导小鼠B细胞对日本血吸虫发育的影响,中国寄生虫学与寄生虫病杂志,2015,33(5):338-344。
2. Zhao QP, Xiong, T,Xu XJ, Jiang MS, Dong HF(董惠芬)*. De Novo transcriptome analysis of Oncomelania hupensis after molluscicide treatment by next-generation sequencing: implications for biology and future snail interventions. PLoS One, 2015, 10(3): e0118673-e0118673.
3. Xiong T, Zhao QP, Xu XJ, Liu R, Jiang MS*, Dong HF(董惠芬)*. Morphological and enzymatical observations in Oncomelania hupensis after molluscicide treatment: implication for future molluscicide development [J]. Parasitol Res, 2016, 115(11): 4139-4152.
4. Gao YR, Zhou XS, Wang H, Liu R, Ye Q, Zhao QP, Ming ZP, Dong HF(董惠芬)*. Immunization with recombinant schistosome adenylate kinase 1 partially protects mice against Schistosoma japonicum infection. Parasitol Res, 2017, 116(6): 1665-1674.
5. Gao YR, Huang WL, Tang CL, Liu R, Zhao QP, Ming ZP, Dong HF(董惠芬) *. Influence of Schistosoma japonicum programmed cell death protein 10 on the growth and development of schistosomula. Parasites & Vectors, 2018, 11(1): 46.
6. Zhao QP, Gao Q, Zhang Y, Li YW, Huang WL, Tang CL, Dong HF(董惠芬)*. Identification of Toll-like receptor family members in Oncomelania hupensis and their role in defense against Schistosoma japonicum. Acta Trop, 2018, 181: 69-78.
7. Liu R, Cheng WJ, Tang HB, Zhong QP, Ming ZP, Dong HF (董惠芬)*. Comparative Metabonomic Investigations of Schistosoma japonicum From SCID Mice and BALB/c Mice: Clues to Developmental Abnormality of Schistosome in the Immunodeficient Host. Front Microbiol, 2019, 10: 440.
8. Wang SH, Li MX, Zhao XJ, Wang H, Zhu J, Wang C, Zhou MS, Dong HF(董惠芬)*, Zhou R*. Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1. FASEB J., 2020, 34(3): 4120-4133.
9. Huang WL, Gu MJ, Cheng WJ, Zhao QP, Ming ZP, Dong HF(董惠芬)*. Characteristics and function of cathepsin L3 from Schistosoma japonicum. Parasitol Res, 2020, 119(5): 1619-1628.
10. Huang WL, Gu MJ, Cheng WJ, Wang SH, Li KJ, Zhao QP, Ming ZP, Dong HF(董惠芬)*. Mechanism by which the combination of SjCL3 and SjGAPDH protects against Schistosoma japonicum infection. Parasitol Res, 2021, 120(1): 173-185.
11. Qu LH, Chen C, Yin T, Fang Q, Hong ZZ, Zhou R, Tang HB*, Dong HF (董惠芬)*. ACE2 and Innate Immunity in the Regulation of SARS-CoV-2-Induced Acute Lung Injury: A Review. Int. J. Mol. Sci. 2021, 22: 11483. https://doi.org/10.3390/ijms222111483
12. Liu R*, Zhong QP, Tang HB, Dong HF (董惠芬)*. Comparative characterization of microRNAs of Schistosoma japonicum From SCID Mice and BALB/c Mice: Clues to the regulation of parasite growth and development. Acta Trop, 2022, 225: 106200.