个人简介

Ph.D., Universite Laval, 1964 Postdoctorate, Davy Faraday Research Laboratory, 1968-70

研究领域

Molecular recognition, surface chemistry and spectroscopy

Our research group aims at understanding the surface chemistry, spectroscopic and microscopic investigation of organic and biological supramolecular complexes. The chemistry of monolayers of supramolecular complexes is of paramount importance on account of many potential applications in diverse fields such as manufacture of new polymers, bio- and chemisensors, protective surface coatings, conductive films, optoelectronic devices, etc. Specifically we are focusing on: Combinatorial chemistry Molecular recognition Development of chemi- and biosensors Tissue engineering Aggregation studies regarding amyloidogenesis

近期论文

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Crawford, N. F., M. Micic, J. Orbulescu, D. Weissbart and R. M. Leblanc, “Surface chemistry and spectroscopy of the β-galactosidase Langmuir monolayer.” Langmuir. 2014 (submitted). Crawford, N. F., J. Orbulescu, D. Weissbart, M. Micic and R. M. Leblanc, “Spectroscopy of β-galactosidase in aqueous phase.” J. Lumin. 2014 (submitted). Zhang, S., N. Pierre-Pierre, S. Li, R. M. Leblanc and Q. Huo. “Protein-gold nanoparticle adsorption assay for prostate cancer detection”. Nanomed: NBM. 2014 (submitted). Sessions, K., S. Sacks, S. Li and R. M. Leblanc. “Epi-fluorescence imaging at the air-water interface of fibrillization of bovine serum albumin and human insulin”. Chem. Commun. 2014, 50, 8955-8957. Li, S., J. Mulloor, L. Wang, Y. Ji, C. J. Mulloor, M. Micic, J. Orbulescu and R. M. Leblanc. “Strong and selective adsorption of lysozyme on graphene oxide”. ACS Appl. Mater. Interfaces. 2014, 6, 5704–5712. Crawford, N. and R. M. Leblanc. “Serum albumin in 2D: a Langmuir monolayer approach”. Adv. Colloid Interface Sci. 2014, 207, 131-138. Li, S., S. Potana, D. J. Keith, C. Wang and R. M. Leblanc. “Isotope-edited FTIR in H2O: determination of the conformation of specific residues in a model α-helix peptide by 13C labeled carbonyls”. Chem. Commun. 2014, 50, 3931–3933. Crawford, N. and R. M. Leblanc. “CdSe and CdSe(ZnS) quantum dots in 2D: a Langmuir monolayer approach”. Coord. Chem. Rev. 2014, 263-264, 13–24. Li, S. and R. M. Leblanc. “Aggregation of insulin at the interface”. J. Phys. Chem. B. 2014, 118 (5), 1181–1188. Li, S. and R. M. Leblanc. “Aggregation of insulin at the interface”. J. Phys. Chem. B. (submitted). Liu, W., Z. Wang, L. Fu, R. M. Leblanc and E. C. Y. Yan. “Lipid compositions modulate fluidity and stability of bilayers: characterization by surface pressure and sum frequency generation spectroscopy”. Langmuir (submitted). Crawford, N. and R. M. Leblanc. “Serum albumin in 2D: a Langmuir monolayer approach”. Adv. Colloid Interface Sci. (accepted). Crawford, N. and R. M. Leblanc. “CdSe and CdSe(ZnS) quantum dots in 2D: a Langmuir monolayer approach”. Coord. Chem. Rev. (in press, DOI 10.1016/j.ccr.2013.07.023). Li, S., J. Guo, R. A. Patel, A. L. Dadlani and R. M. Leblanc. “Interaction between graphene oxide and pluronic F127 at the air-water interface”. Langmuir 29, 5742-5748. Li, S., A. Stein, A. Kruger and R. M. Leblanc. “Head groups of lipids govern the interaction and orientation between graphene oxide and lipids”. J. Phys. Chem. 117 (31), 16150-16158. Li, S., A. M. Othman and R. M. Leblanc. “Enhancing selectivity in spectrofluorimetric determination of trytophan by using graphene oxide”. Anal. Chim. Acta 787, 226-232. Xu, J., C. Wang, J. Wang, Q. Huo, N. F. Crawford, E. A. Véliz and R. M. Leblanc. “Smooth surface roughness of silanized CdSe(ZnS) quantum dots”. J. Colloid Interface Sci. 393, 21-28. Djikanovic, D., A. Kalauzi, M. Jeremic, J. Xu, M. Micic, J. Whyte, R. M. Leblanc and K. Radotic. “Interaction of the CdSe quantum dots with plant cell walls”. Colloids Surf., B: Biointerfaces 91, 41-47. Garcia, A. R., I. Rahn, S. Johnson, R. Patel, J. Guo, J. Orbulescu, M. Micic, P. Blackwelder and R. M. Leblanc. “Human insulin fibril-assisted synthesis of fluorescent gold nanoclusters in alkaline media under physiological temperature”. Coll. Surf., B: Biointerfaces 105, 165-172. Johnson, S., W. Liu, G. Thakur, A. Dadlani, R. Patel, J. Orbulescu, J. Whyte, M. Micic and R. M. Leblanc. “Surface chemistry and spectroscopy of human insulin Langmuir monolayer”. J. Phys. Chem. B. 116 (34), 10205-10212.