刘向东 - 东南大学 - 生命科学与技术研究院

个人简介

1985年毕业于厦门大学生物系生物化学专业，获理学学士学位 1991年毕业于北京协和医学院临床化学专业，获理学硕士学位 1999年毕业于丹麦奥尔胡斯大学（Aarhus University）公共卫生学院，获博士学位

研究领域

(1)自身免疫性肝病的病因学研究 (2)肥厚型心肌病致病基因的筛选和功能分析

近期论文

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1．Wang C*, Zheng X*, Jiang P*, Tang R*, Gong Y*, Dai Y*, Wang L*, Xu P*, Sun W, Wang L, Han C, Jiang Y, Wei Y, Zhang K, Wu J, Shao Y, Gao Y, Yu J, Hu Z, Zang Z, Zhao Y, Wu X, Dai N, Liu L, Nie J, Jiang B, Lin M, Li L, Li Y, Chen S, Shu L, Qiu F, Wu Q, Zhang M, Chen R, Jawed R, Zhang Y, Shi X, Zhu Z, Pei H, Huang L, Zhao W, Tian Y, Zhu X, Qiu H, M. Gershwin ME, Chen W, Seldin MF, Liu X#†, Sun L#, Ma X#. Genome Wide Association Studies of Specific Antinuclear Autoantibody Sub-phenotypes in Primary Biliary Cholangitis. Hepatology, 2019 Mar 10. doi: 10.1002/hep.30604. [Epub ahead of print] (*共同第一作者, #共同通讯作者, †第一通讯作者) 2．Qiu F*, Tang R*, Zuo X*, Shi X*, Wei Y*, Zheng X*, Dai Y, Gong Y, Wang L, Xu P, Zhu X, Wu J, Han C, Gao Y, Zhang K, Jiang Y, Zhou J, Shao Y, Hu Z, Tian Y, Zhang H, Dai N, Liu L, Wu X, Zhao W, Zhang X, Zang Z, Nie J, Sun W, Zhao Y, Mao Y, Jiang P, Ji H, Dong Q, Li J, Li Z, Bai X, Li L, Lin M, Dong M, Li J, Zhu P, Wang C, Zhang Y, Jiang P, Wang Y, Jawed R, Xu J, Zhang Y, Wang Q, Yang Y, Yang F, Lian M, Jiang X, Xiao X, Li Y, Fang J, Qiu D, Zhu Z, Qiu H, Zhang J, Tian W, Chen S, Jiang L, Ji B, Li P, Chen G, Wu T, Sun Y, Yu J, Tang H, He M, Xia M, Pei H, Huang L, Qing Z, Wu J, Huang Q, Han J, Xie W, Sun Z, Guo J, He G, Eric Gershwin M, Lian Z, Liu X, Seldin MF, Liu X#†, Chen W#, Ma X#. A genome-wide association study identifies six novel risk loci for primary biliary cholangitis. Nat Commun. 2017 Apr 20;8:14828. doi: 10.1038/ncomms14828. (*共同第一作者, #共同通讯作者, †第一通讯作者) 3．Xu J, Li Z, Ren X, Dong M, Li J, Shi X, Zhang Y, Xie W, Sun Z, Liu X*†, Dai Q*. Investigation of Pathogenic Genes in Chinese sporadic Hypertrophic Cardiomyopathy Patients by Whole Exome Sequencing. Sci Rep. 2015 Nov 17;5:16609. (*共同通讯作者, †第一通讯作者) 4．Dong M, Li JX, Tang RQ, Zhu P, Qiu F, Wang C, Qiu J, Wang L, Dai YP, Xu P, Gao YQ, Han CX, Wang YZ, Wu J, Wu XD, Zhang K, Dai N, Sun WH, Zhou JB, Hu ZG, Liu L, Jiang YZ, Nie JS, Zhao Y, Gong YH, Tian Y, Ji HL, Jiao ZJ, Jiang P, Shi XJ, Jawed R, Zhang Y, Huang QH, Li EL, Wei YR, Xie W, Zhao WF, Liu X, Zhu X, Qiu H, He GS, Chen WC, Seldin MF, Gershwin EM*, Liu XD*†, Ma X*. Multiple genetic variants associated with primary biliary cirrhosis in a Han Chinese population#. Clin Rev Allerg Immunol. 2015 Jun;48(2-3):316-21.（*共同通讯作者, †第一通讯作者, #original article） 5．Liu XD*, Invernizzi P*, Lu Y, Kosoy R, et al., Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. Nat Genet. 2010, 42(8):658-60. (*共同第一作者) 6．Hirschfield GM, Liu XD, Han YH, Gorlov IP, et al., Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. Nat Genet. 2010, 42(8):655-7. 7．Hirschfield GM*, Liu XD*, Xu C, Lu Y, Xie G, et al., Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med. 2009, 360(24):2544-55. (*共同第一作者)