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个人简介

生物材料与组织工程专业博士,生物医学工程专业博士后。曾入选首批国家博士后国际交流计划派出项目(2013年);主持完成国家自然科学基金青年项目和面上项目各1项,参与国家自然科学基金项目6项。已在Journal of Materials Chemistry A、Biomaterials、Bioactive Materials、Nanoscale、Small、Autophagy等SCI期刊发表研究论文30余篇;相关成果被Chemical Reviews、ACS Nano、Biomaterials、Small、PRL、Journal of Materials Chemistry A、Nanoscale、Acta Biomaterialia、ACS Applied Materials and Interface等国际高水平期刊他引1000多次,H-index:17。现阶段研究兴趣主要在贵金属纳米酶及荧光成像、常温液态金属材料及器件、仿生/遗态材料及矿化等领域。 教育经历: 1. 2005.3~2010.6 东南大学材料科学与工程学院,生物材料与组织工程专业,工学博士,导师:林萍华教授,董寅生教授 2. 2002.9~2005.3 东南大学材料科学与工程学院,材料加工工程专业,工学硕士,导师:林萍华教授,董寅生教授 3. 1998.9~2002.6 东南大学机械工程系,材料成型及控制工程专业(主修)/工业管理工程专业(辅修),工学学士,本科优秀毕业生,指导老师:高锦张副教授,戴挺副教授 工作经历: Ø 2020.9~今,材料学院材料加工工程系,副系主任 Ø 2019.5~今,东南大学材料科学与工程学院,副教授 Ø 2016.12~2022.9,江苏省先进金属材料高技术研究重点实验室,秘书(兼职) Ø 2016.12~2019.4,东南大学材料科学与工程学院,讲师 Ø 2014.5~2016.12,密西根大学化学系/东南大学生物科学与医学工程学院,博士后 Ø 2010.7~2014.5,东南大学生物科学与医学工程学院,生物医学工程专业,博士后 教学课程: 1. 工程金属材料,能源与环境学院,32学时 2. 材料工程测试技术,材料科学与工程学院,48学时 3. 科技论文读写,材料科学与工程学院,32学时 4. 工业实习,材料科学与工程学院,16学时 5. 材料工业项目选型与设计,材料科学与工程学院,研究生课程,32学时 6. 功能材料导论,研究生课程,32学时

研究领域

1. 多功能贵金属基纳米材料 2. 常温液态金属生物医学材料 3. 仿生/遗态材料及矿化 4. 生物材料与组织工程 5. 材料先进加工制备技术

近期论文

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1. Linyuan Han, Zhenwei Zhang, Jianwei Dai, Xuan Li, Jing Bai, Zhihai Huang, Chao Guo, Feng Xue, Chenglin Chu. The influence of alternating cyclic dynamic loads with different low frequencies on the bio-corrosion behaviors of AZ31B magnesium alloy in vitro[J]. Bioactive Materials, 2022, 7: 263-274 2. Jinglong Feng, Zhihai Huang, Yinsheng Dong. Preparation of ice microspheres and their application in the preparation of porous poly(L-lactic acid) (PLLA) scaffolds[J]. Journal of Materials Science, 2019, 54(4): 3661-3670 3. Jinglong Feng, Zhihai Huang, Yinsheng Dong. Effect of mixed solvents on the thermal properties of poly(L-lactic acid) (PLLA) solution and micromorphology of porous PLLA scaffolds[J]. Materials Research Express, 2019, 015314 4. Xulong An, Hui Zhao, Ting Dai, Hongguang Yu, Zhihai Huang, Chao Guo, Paul K. Chu, Chenglin Chu. Effects of heat treatment on the microstructure and properties of cold-forged CoNiFe medium entropy alloy[J]. Intermetallics, 2019, 110: 106477 5. Xulong An, Hui Zhao, Chenglin Chu, Ting Dai, Tao Lu, Zhihai Huang, Chao Guo, Paul K Chu. Hall-Petch relationship and corrosion behavior of cold-rolled CoNiFe medium entropy alloy[J]. Journal of Alloys and Compounds, 2019, 807: 151698 6. Jun Lin, Yiming Liu, Hao Wu, Zhihai Huang, Jingfan Ma, Chang Guo, Feng Gao, Peipei Jin, Pengfei Wei, Yunjiao Zhang, Liu Liu, Rui Zhang, Longxin Qiu, Ning Gu, Longping Wen. Key Role of TFEB Nucleus Translocation for Silver Nanoparticle-Induced Cytoprotective Autophagy[J]. Small, 2018, 13(14): 1703711(1-10) 7. Lingying Zhu, Dawei Guo (co-first author), Lili Sun, Zhihai Huang, Xiuyan Zhang, Wenjuan Ma, Jie Wu, Lu Xiao, Yun Zhao, Ning Gu. Activation of autophagy by elevated reactive oxygen species rather than released silver ions promotes cytotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in hematopoietic cells[J]. Nanoscale, 2017, 9(17): 5489-5498 8. Qi Ding, Dongfang Liu, Dawei Guo, Fang Yang, Xingyun Pang, Renchao Che, Naizhen Zhou, Jun Xie, Jianfei Sun, Zhihai Huang, Ning Gu. Shape-controlled fabrication of magnetite silver hybrid nanoparticles with high performance magnetic hyperthermia[J]. Biomaterials, 2017, 124: 35-46 9. Hao Wu, Jun Lin, Peidang Liu, Zhihai Huang, Peng Zhao, Haizhen Jin, Jun Ma, Longping Wen, Ning Gu. Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs[J]. Biomaterials, 2016, 101: 1-9 10. Zhihai Huang, Hao Jiang, Peidang Liu, Jianfei Sun, Dawei Guo, Jieling Shan, Ning Gu. Continuous synthesis of size-tunable silver nanoparticles by green electrolysis method and multi-electrode design for high yield[J]. Journal of Materials Chemistry A, 2015, 3: 1925-1929 11. Hao Wu, Jun Lin, Peidang Liu, Zhihai Huang, Peng Zhao, Haizhen Jin, Cailian Wang, Longping Wen, Ning Gu. Is the autophagy a friend or foe in the silver nanoparticles associated radiotherapy for glioma?[J]. Biomaterials, 2015, 62: 47-57 12. Dawei Guo, Dandan Dou, Lin Ge, Zhihai Huang, Liping Wang, Ning Gu. A caffeic acid mediated facile synthesis of silver nanoparticles with powerful anti-cancer activity[J]. Colloids and Surfaces B: Biointerfaces, 2015, 134: 229-234 13. Dawei Guo, Junren Zhang, Zhihai Huang, Shanxiang Jiang, Ning Gu. Colloidal silver nanoparticles improves anti-leukemic drug efficacy via amplification of oxidative stress[J]. Colloids and Surfaces B: Biointerfaces, 2015, 126: 198-203 14. Jun Lin, Zhihai Huang, Hao Wu, Wei Zhou, Peipei Jin, Pengfei Wei, Yunjiao Zhang, Fang Zheng, Jiqian Zhang, Jing Xu, Yi Hu, Yanhong Wang, Yajuan Li, Ning Gu, Longping Wen. Inhibition of autophagy enhances the anticancer activity of silver nanoparticles[J]. Autophagy, 2014, 10(11): 2006-2020 15. Dawei Guo, Yun Zhao, Yu Zhang, Qing Wang, Zhihai Huang, Qi Ding, Zhirui Guo, Xuefeng Zhou, Lingying Zhu, Ning Gu, The Cellular Uptake and Cytotoxic Effect of silver Nanoparticles on Chronic Myeloid Leukemia Cells[J]. Journal of Biomedical Nanotechnology, 2014, 10(4): 669-678 16. Peidang Liu, Zhihai Huang (co-first author), Zhongwen Chen, Ruizhi Xu, Hao Wu, Fengchao Zang, Cailian Wang, Ning Gu. Silver nanoparticles: a novel radiation sensitizer for glioma?[J]. Nanoscale, 2013, 5: 11829-11836 17. Zhihai Huang, Qing Wang, Zhirui Guo, Lina Xu, Dongfang Liu, Qi Ding, Ning Gu. Rapid synthesis of high-stable silver nanoparticles by electrochemical method[J]. Nanoscience and Nanotechnology Letters, 2013, 5(2): 232-236 18. Dawei Guo, Lingying Zhu, Zhihai Huang, Haixia Zhou, Yue Ge, Wenjuan Ma, Jie Wu, Xiuyan Zhang, Xuefeng Zhou, Yu Zhang, Yun Zhao, Ning Gu. Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions[J]. Biomaterials, 2013, 34(32): 7884-7894 19. Peidang Liu, Zhihai Huang, Ning Gu. Exposure to silver nanoparticles does not affect cognitive outcome or hippocampal neurogenesis in adult mice[J]. Ecotoxicology and Environmental Safety, 2013, 87: 124-130 20. Jun Dou, Xiangfeng He (co-first author), Yunjing Liu (co-first author), Zhihai Huang, Cuiping Yang, Fangfang Shi, Dengyu Chen, Ning Gu. Targeted therapeutic effect of anti-ABCG2 antibody combined with nano silver and vincristine on mouse myeloma cancer stem cells[J]. Journal of Nanoparticle Research, 2013, 15: 2127-2141 21. Dawei Guo, Xiuyan Zhang (co-first author), Zhihai Huang, Xuefeng Zhou, Lingying Zhu, Yun Zhao, Ning Gu. Comparison of cellular responses across multiple passage numbers in Ba/F3-BCR-ABL cells induced by silver nanoparticles[J]. Science China (Life Sciences), 2012, 55(10), 898-905 22. Zhihai Huang, Xiaoli Jiang, Dawei Guo, Ning Gu. Controllable synthesis and biomedical applications of silver nanomaterials[J]. Journal of Nanoscience and Nanotechnology, 2011, 11: 9395-9408 23. Zhihai Huang, Yinsheng Dong, Pinghua Lin. Depositing an Apatite Coating in/on Massive Chitosan Porous Scaffolds by an Alternate Soaking Method[J]. Acta Physico-Chimica Sinica, 2009, 25(7): 1285-1289 (in Chinese) 24. Zhihai Huang,Jihong Li, Pinghua Lin, Yinsheng Dong, Chao Guo, Xiaobo Sheng, Chenglin Chu. Electrochemistry assisted depositing hydroxyapatite coating in chitosan porous scaffold[J]. Acta Polymerica Sinica, 2009, (3): 273-277 (in Chinese) 25. Zhihai Huang, Yinsheng Dong, Chenglin Chu, Pinghua Lin. Electrochemistry assisted reacting deposition of hydroxyapatite in porous chitosan scaffolds[J]. Materials Letters, 2008, 62(19): 3376-3378 26. Zhihai Huang, Lei Yang, Yinsheng Dong, Pinghua Lin. Fabrication of chitosan sponge as dressings by phase separation-extraction method[J]. The Chinese Journal of Nonferrous Metals, 2007, 17(s1): 268-274 (in Chinese) 27. Zhihai Huang, Yinsheng Dong, Chao Guo, Pinghua Lin. Study of freeze-drying process of natural polymer porous scaffolds[J]. Journal of China Biotechnology, 2004, 24(11): 76-79 (in Chinese) 28. Zhihai Huang, Yinsheng Dong, Chao Guo, Pinghua Lin. Study on fabrication of porous chitosan-collagen scaffolds[J]. Chemical Industry Times, 2004, 18(10): 36-39 (in Chinese)

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