Streichan, Sebastian - University of California, Santa Barbara

研究领域

We use ideas and concepts from physics, computer science, and mathematics to ask how embryos get in shape, and how organs function. To answer our questions, we develop and use methods that enable quantitative analysis at the level of whole organs.

近期论文

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Streichan SJ, Lefebvre MF, Noll N, Wieschaus EF, Shraiman BI. 2018. Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors.. Elife. 7 Noll N, Mani M, Heemskerk I, Streichan SJ, Shraiman BI. 2017. Active tension network model suggests an exotic mechanical state realized in epithelial tissues. Nature Physics. 153:948–7. Lignell A, Kerosuo L, Streichan SJ, Cai L, Bronner ME. 2017. Identification of a neural crest stem cell niche by Spatial Genomic Analysis.. Nat Commun. 8(1):1830. Streichan SJ, Lefebvre MF, Noll N, Wieschaus EF, Shraiman BI. 2017. Quantification of myosin distribution predicts global morphogenetic flow in the fly embryo. arXiv.org. Chan KG, Streichan SJ, Trinh LA, Liebling M. 2016. Simultaneous Temporal Superresolution and Denoising for Cardiac Fluorescence Microscopy. IEEE Transactions on Computational Imaging. 2:348–358. Chen D-Y, Lipari KR, Dehghan Y, Streichan SJ, Bilder D. 2016. Symmetry Breaking in an Edgeless Epithelium by Fat2-Regulated Microtubule Polarity.. Cell Rep. 15(6):1125-33. Heemskerk I, Streichan SJ. 2015. Tissue cartography: compressing bio-image data by dimensional reduction.. Nat Methods. 12(12):1139-42. Revenu C, Streichan S, Donà E, Lecaudey V, Hufnagel L, Gilmour D. 2014. Quantitative cell polarity imaging defines leader-to-follower transitions during collective migration and the key role of microtubule-dependent adherens junction formation.. Development. 141(6):1282-91. Streichan SJ, Hoerner CR, Schneidt T, Holzer D, Hufnagel L. 2014. Spatial constraints control cell proliferation in tissues.. Proc Natl Acad Sci U S A. 111(15):5586-91.