个人简介

2004-: University of British Columbia; 2001-2004: University of California, Berkeley (Postdoc); 1994-2001: University of California, Riverside (PhD, 2001); 1993-1994: Brown University; 1992,1993: L3 Experiment, CERN; 1991-1993: National Central University (MS, 1993); 1985-1989: Tunghai University (BS, 1989)

研究领域

Chemical Physics; Interfacial and Surface Chemistry; Physical & Theoretical Chemistry

Our research is devoted to the application of nonlinear optical spectroscopy in surface chemistry, materials science and biophysical chemistry: (I) Nanoscale Far-field Microscopy for Research in Biological and Material Science Because of the diffraction limit, the resolution of a far-field fluorescent microscope is limited to 200-300 nm, which makes it unable to resolve many fine structures. We have developed a two-photon excitation fluorescence (2PEF) microscope with 55-nm resolution. We study biological and material science problems with the nanoscale optical microscope. (II) Oilsands Surface Chemistry Canada’s oilsands reserves, which are estimated at 175 billion barrels, place Canada second in the world ranking of crude oil reserves. However, the large amount of water used in current bitumen extraction processes is a great concern, particularly as the industry is expected to grow over the next 20 years. Our research objective is to understand the competition adsorption of solvents, water, and bitumen on mineral materials to provide molecular-level information for developing a more environment-friendly extraction process. This research project is funded by the Imperial Oil-Alberta Ingenuity Centre for Oil Sands Innovation. More information can be found at www.cosi.ca Videos about the Alberta oil sands (III) Surface Properties of Materials Surface properties of materials are often different from those for the bulk, and they play an important role in many natural and industrial processes. The surfaces of polymers, for example, have very different molecular structures from the bulks. These structural differences can lead to different phase transition properties and different optical and electronic properties. (IV) Surface Chemistry at Aqueous and Electrochemical Interfaces As water is often considered the most important solvent, a molecular-level understanding of aqueous interfaces is critical for understanding many environmental, chemical and biological processes. However, because of the difficulties to probe a buried aqueous interface, our understanding of the buried aqueous interface is still limited. Our group uses sum frequency generation vibrational spectroscopy to probe the structures of water molecules and their interactions with the substrates.

近期论文

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Tsou, C. - J. ; Hsia, C. - H. ; Chu, J. - Y. ; Hung, Y. ; Chen, Y. - P. ; Chien, F. - C. ; Chou, K. C. ; Chen, P. ; Mou, C. - Y. Local Ph Tracking In Living Cells. Nanoscale 2015, 7, 4217-25.BibTex 2014 Hu, D. ; Chou, K. C. Re-Evaluating The Surface Tension Analysis Of Polyelectrolyte-Surfactant Mixtures Using Phase-Sensitive Sum Frequency Generation Spectroscopy. Journal of the American Chemical Society 2014, 136, 15114-15117.BibTex Shih, J. - Y. ; Huang, W. - C. ; Ko, C. - T. ; Yang, Z. ; Hu, S. - H. ; Leu, J. ; Chou, K. C. ; Chen, K. - N. Adhesion Investigation Between Metal And Benzocyclobutene (Bcb) Polymer Dielectric Materials In 3-D Integration Applications. Ieee Transactions on Device and Materials Reliability 2014, 14, 914-920.BibTex 2013 Hu, D. ; Yang, Z. ; Chou, K. C. Interactions Of Polyelectrolytes With Water And Ions At Air/water Interfaces Studied By Phase-Sensitive Sum Frequency Generation Vibrational Spectroscopy. Journal of Physical Chemistry C 2013, 117, 15698-15703.BibTex Leung, J. P. ; Wu, S. ; Chou, K. C. ; Signorell, R. Investigation Of Sub-100 Nm Gold Nanoparticles For Laser-Induced Thermotherapy Of Cancer. Nanomaterials 2013, 3, 86-106.BibTex 2012 Leung, B. O. ; Yang, Z. ; Wu, S. S. H. ; Chou, K. C. Role Of Interfacial Water On Protein Adsorption At Cross-Linked Polyethylene Oxide Interfaces. Langmuir 2012, 28, 5724-5728.BibTex 2011 Leung, B. O. ; Chou, K. C. Review Of Super-Resolution Fluorescence Microscopy For Biology. Applied Spectroscopy 2011, 65, 967-980.BibTex Yang, Z. ; Bertram, A. K. ; Chou, K. C. Why Do Sulfuric Acid Coatings Influence The Ice Nucleation Properties Of Mineral Dust Particles In The Atmosphere?. Journal of Physical Chemistry Letters 2011, 2, 1232-1236.BibTex 2010 Yang, Z. ; Li, Q. ; Gray, M. R. ; Chou, K. C. Structures Of Water Molecules At Solvent/silica Interfaces. Langmuir 2010, 26, 16397-16400.BibTex 2009 Yang, Z. ; Li, Q. F. ; Hua, R. ; Gray, M. R. ; Chou, K. C. Competitive Adsorption Of Toluene And N-Alkanes At Binary Solution/silica Interfaces. Journal of Physical Chemistry C 2009, 113, 20355-20359.BibTex Yang, Z. ; Li, Q. F. ; Chou, K. C. Structures Of Water Molecules At The Interfaces Of Aqueous Salt Solutions And Silica: Cation Effects. Journal of Physical Chemistry C 2009, 113, 8201-8205.BibTex Li, Q. F. ; Wu, S. S. H. ; Chou, K. C. Subdiffraction-Limit Two-Photon Fluorescence Microscopy For Gfp-Tagged Cell Imaging. Biophysical Journal 2009, 97, 3224-3228.BibTex Li, Q. F. ; Kuo, C. W. ; Yang, Z. ; Chen, P. L. ; Chou, K. C. Surface-Enhanced Ir-Visible Sum Frequency Generation Vibrational Spectroscopy. Physical Chemistry Chemical Physics 2009, 11, 3436-3442.BibTex Weiss, A. ; Preston, T. C. ; Popov, J. ; Li, Q. ; Wu, S. ; Chou, K. C. ; Burt, H. M. ; Bally, M. B. ; Signorell, R. Selective Recognition Of Rituximab-Functionalized Gold Nanoparticles By Lymphoma Cells Studied With 3D Imaging. Journal of Physical Chemistry C 2009, 113, 20252-20258.BibTex 2008 Pietrangelo, A. ; Sih, B. C. ; Boden, B. N. ; Wang, Z. W. ; Li, Q. F. ; Chou, K. C. ; MacLachlan, M. J. ; Wolf, M. O. Nonlinear Optical Properties Of Schiff-Base-Containing Conductive Polymer Films Electro-Deposited In Microgravity. Advanced Materials 2008, 20, 2280-+.BibTex Li, Q. F. ; Hua, R. ; Cheah, I. J. ; Chou, K. C. Surface Structure Relaxation Of Poly(Methyl Methacrylate). Journal of Physical Chemistry B 2008, 112, 694-697.BibTex Li, Q. ; Hua, R. ; Chou, K. C. Electronic And Conformational Properties Of The Conjugated Polymer Meh-Ppv At A Buried Film/solid Interface Investigated By Two-Dimensional Ir-Visible Sum Frequency Generation. Journal of Physical Chemistry B 2008, 112, 2315-2318.BibTex 2005 Stamenkovic, V. ; Chou, K. C. ; Somorjai, G. A. ; Ross, P. N. ; Markovic, N. M. Vibrational Properties Of Co At The Pt(111)-Solution Interface: The Anomalous Stark-Tuning Slope. Journal of Physical Chemistry B 2005, 109, 678-680.BibTex 2004 Westerberg, S. ; Wang, C. ; Chou, K. ; Somorjai, G. A. High-Pressure Ammonia Adsorption And Dissociation On Clean Fe(111) And Oxygen-Precovered Fe(111) Studied By Sum Frequency Generation Vibrational Spectroscopy. Journal of Physical Chemistry B 2004, 108, 6374-6380.BibTex Yang, M. C. ; Chou, K. C. ; Somorjai, G. A. The Structures And Reactions Of Linear And Cyclic C-6 Hydrocarbons Adsorbed On The Pt(111) Crystal Surface By Sum Frequency Generation Vibrational Spectroscopy Pressure, Temperature, And H-2 Coadsorption Effects. Journal of Physical Chemistry B 2004, 108, 14766-14779.BibTex Chou, K. C. ; Westerberg, S. ; Shen, Y. R. ; Ross, P. N. ; Somorjai, G. A. Probing The Charge-Transfer State Of Co On Pt(111) By Two-Dimensional Infrared-Visible Sum Frequency Generation Spectroscopy. Physical Review B 2004, 69.BibTex 2003 Kim, J. ; Chou, K. C. ; Somorjai, G. A. Structure And Dynamics Of Acetonitrile At The Air/liquid Interface Of Binary Solutions Studied By Infrared-Visible Sum Frequency Generation. Journal of Physical Chemistry B 2003, 107, 1592-1596.BibTex Kim, J. ; Opdahl, A. ; Chou, K. C. ; Somorjai, G. A. Hydrophobic-Interaction-Induced Alignment Of Polymers At The Solid/liquid Interface Studied By Infrared-Visible Sum Frequency Generation. Langmuir 2003, 19, 9551-9553.BibTex Yang, M. ; Chou, K. C. ; Somorjai, G. A. In-Situ Observation Of Pi-Allyl C-C6H9 Intermediate During High-Pressure Cyclohexene Catalytic Reactions On Pt(111) Using Sum Frequency Generation Vibrational Spectroscopy. Journal of Physical Chemistry B 2003, 107, 5267-5272.BibTex Chou, K. C. ; Kim, J. ; Baldelli, S. ; Somorjai, G. A. Vibrational Spectroscopy Of Carbon Monoxide, Acetonitrile, And Phenylalanine Adsorbed On Liquid Vertical Bar Electrode Interfaces By Sum Frequency Generation. Journal of Electroanalytical Chemistry 2003, 554, 253-263.BibTex Chou, K. C. ; Markovic, N. M. ; Kim, J. ; Ross, P. N. ; Somorjai, G. A. An In Situ Time-Dependent Study Of Co Oxidation On Pt(111) In Aqueous Solution By Voltammetry And Sum Frequency Generation. Journal of Physical Chemistry B 2003, 107, 1840-1844.BibTex