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教育经历 2011年8月-2015年6月:博士后,美国斯克利普斯研究所 2006年8月-2011年7月:博士,美国亚利桑那州立大学 2004年9月-2006年7月:硕士,浙江大学 2000年9月-2004年7月:学士,浙江大学

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Nannan Chen, Liping Zhu, Lu Gan, Zhenquan Liu, Rui Wang, Xiaoqing Cai*, Xianxing Jiang, Asymmetric synthesis of bispiro[r-butyrolactone-pyrrolidin-4,4'-pyrozolone] scaffolds containg two quarternary spirocenters via an organocatalytic 1,3-dipolar cycloaddition, European Journal of Organic Chemistry, 2939-2943, 2018. X. Cai, K. Tsuchikama, K. D. Janda*, Modulating anti-cocaine vaccine potency through hapten fluorination, Journal of the American Chemical Society, 135, 2971–2974, 2013. X. Cai, T. Whitfield, M. S. Hixon, Y. Grant, G. F. Koob, K. D. Janda*, Probing active cocaine vaccination performance through catalytic and noncatalytic hapten design, Journal of Medicinal Chemistry, 56, 3701–3709, 2013. X. Cai, T. Whitfield, A. Y. Moreno, Y. Grant, M. S. Hixon, G. F. Koob, K. D. Janda*, Probing the effects of hapten stability on cocaine vaccine immunogenicity, Molecular Pharmaceutics, 10, 4176–4184, 2013. C. J. Wenthur, X. Cai, B. A. Ellis, K. D. Janda*, Augmenting the efficacy of anti-cocaine catalytic antibodies through chimeric hapten design and combinatorial vaccination, Bioorganic & Medicinal Chemistry Letters, 15, 3666-3668, 2017. J. Zhu, X. Cai, T. Harris, M. Gooyit, M. Wood, M. Lardy, K. D. Janda*, Disarming Pseudomonas aeruginosa virulence factor LasB by leveraging a Caenorhabditis elegans infection model. Chemistry & Biology, 22, 483–491, 2015. J. Lu, X. Cai, S. M. Hecht*, Concise synthesis of bicyclic pyridinol antioxidants, Organic Letters, 12, 5189–5191, 2010. X. Cai, K. D. Janda*, A chemoenzymatic approach toward the preparation of site-specific antibody-drug conjugates, Tetrahedron Letters, 56, 3172–3175, 2015. X. Cai, O. M. Khdour, J. Jaruvangsanti, S. M. Hecht*, Simplified bicyclic pyridinol analogues protect mitochondrial function, Bioorganic & Medicinal Chemistry, 20, 3584–3595, 2012. X. Cai, P. Zaleski, A. Cagir, S. M. Hecht, Deglycobleomycin A6 analogues modified in the methylvalerate moiety, Bioorganic & Medicinal Chemistry, 19, 3831–3844, 2011. X. Cai, N. Wang, X. Lin, Chemo-enzymatic synthesis of optically active polymeric prodrug of Naproxen, Ketoprofen and Ibuprofen, Polymer, 47, 6491–6495, 2006. X. Cai, N. Wang, X. Lin*, The preparation of polymerizable, optically active-non-steroidal anti-inflammatory drugs derivatives by irreversible enzymatic methods, Journal of Molecular Catalysis. B, Enzymatic, 40, 51–57, 2006. X. Cai, Z. Chen, N. Wang, X. Lin*, A facile method for preparation of polymerizable Optically active Ketoprofen prodrug by irreversible lipase-catalyzed resolution, World Journal of Microbiology & Biotechnology, 22, 723–727, 2006. L. M. Eubanks, B. A. Ellis, X. Cai, J. E. Schlosburg, K. D. Janda*, A human recombinant monoclonal antibody to cocaine: preparation, characterization and behavioral studies, Bioorganic & Medicinal Chemistry Letters, 24, 4664–4666, 2014. J. L. Fullagar, A. L. Garner, A. K. Struss, J. A. Day, D. P. Martin, J. Yu, X. Cai, K. D. Janda*, S. M. Cohen*, Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase, Chemical Communications, 49, 3197–3199, 2013. J. C. Chapuis, O. M. Khdour, X. Cai, J. Lu, S. M. Hecht*, Synthesis and characterization of ∆lac-acetogenins that potently inhibit mitochondrial complex I, Bioorganic & Medicinal Chemistry, 17, 2204–2209, 2009. J. Quan, N. Wang, X. Cai, Q. Wu, X. Lin*, Controllable selective enzymatic synthesis of N-acyl and O-acylpropranolol vinyl esters and preparation of polymeric prodrug of propranolol, Journal of Molecular Catalysis. B, Enzymatic, 44, 1–7, 2007. Q. Wu*, Q. Chen, X. Cai, J. Wang, J. Zhang, Preparation and conductivity of solid high-proton conductor silica gel containing 80 wt.% decatungstodivanadogermanic acid, Materials Letters, 61, 663–665, 2007. Q. Wu*, X. Cai, W. Feng, W. Pang, Thermal stability of ternary transition metal heteropoly complexes, Thermochimica Acta, 428, 15–18, 2005.

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