Manns, Fabrice - University of Miami - Biomedical Engineering

个人简介

Dr. Manns is a professor of biomedical engineering and ophthalmology and the chair of the Department of Biomedical Engineering, where he has also previously served as associate chairman and graduate program director. He has been a University of Miami faculty member since 1997. Manns divides his time between the Coral Gables campus and the Medical campus, where he is the co-director of Bascom Palmer Eye Institute’s Ophthalmic Biophysics Center. The Ophthalmic Biophysics Center is a research laboratory founded in 1970 by Prof. Jean-Marie Parel and is dedicated to the development of technologies designed to improve patient eye care. Manns leads a research program in the broad field of biomedical optics, including studies on the optics of the eye. His current research activities are the development of optical imaging and biometry systems to study the mechanism of accommodation and presbyopia and the relationship between the optics and anatomy of the eye to help optimize vision-correction procedures. He has also collaborated with clinicians on the development of laser and optical instrumentation for treatment or diagnosis of diseases in the fields of breast cancer, urology and otolaryngology. He has served as a lead investigator on both federally funded and industry-sponsored projects. Manns teaches undergraduate and graduate courses on medical imaging, biomedical optical instrumentation and imaging, medical applications of lasers, and optics of the eye. He also is an instructor in Bascom Palmer Eye Institute’s master’s program in visual science and investigative ophthalmology, where he coordinates a course on visual optics. Manns has been the chair of SPIE’s Ophthalmic Technologies Conference since 1997. He is an associate editor of the Optical Society of America’s Biomedical Optics Express journal and serves on the program committee of the annual meeting of the International Society for Imaging in the Eye. Manns received an electrical engineering degree from the Ecole Nationale Supérieure d’Electronique et de Radioélectricité de Bordeaux (now ENSEIRB MATMECA) and a post-graduate degree from the University of Bordeaux in microelectronics. He earned his PhD in biomedical engineering from the University of Miami. He completed a post-doctoral fellowship at Bascom Palmer Eye Institute sponsored by Fight for Sight before being hired as a faculty member jointly by the Department of Biomedical Engineering and the Department of Ophthalmology in 1997. University of Miami, PhD in Biomedical Engineering. (1996) University of Bordeaux I, Bordeaux, France, MS in Diplome d'Etudes Appronfondies. (1991) Ecole Nationale Superieure d'Electronique et de Radioelectricite de Bordeaux, Bordeaux, France, BS in Electrical Engineering. (1991) University of Miami, Professor. (2013 - Present) University of Miami, Co-Director. (2001 - Present) University of Miami, Director. (1997 - Present) University of Miami, Graduate Program Director. (2009 - 2016) University of Miami, Associate Chairman. (2008 - 2016) University of Miami, Acting Chair. (2013 - 2014) University of Miami, Associate Professor (with tenure). (2006 - 2013) University of Miami, Assistant Professor. (2000 - 2006) University of Miami, Manager. (1995 - 2001) University of Miami, Research Assistant Professor. (1997 - 2000) University of Miami, Adjunct Instructor. (1996 - 1997) University of Miami, Post-doctoral Associate. (1996 - 1997) University of Miami, Graduate Research Assistant. (1992 - 1996) University of Bordeaux I, Research Engineer. (1991 - 1992) University of Bordeaux I, Research Assistant. (1991) European Molecular Biology Laboratory, Heidelberg, Germany, Trainee. (1990)

研究领域

Laser applications in medicine, Biomedical optical imaging, Optics of the eye and vision correction, Ophthalmic technologies

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Wu, C., Han, Z., Wang, S., Li, J., Singh, M., Liu, C., Aglyamov, S., Emelianov, S., Manns, F., Larin, K. V. (2015). Assessing age-related changes in the biomechanical properties of rabbit lens using a co-aligned ultrasound and optical coherence elastography system. Investigative Ophthalmology and Visual Science, 56, 1292-1300. De Freitas, C., Cabot, F., Culbertson, W., Yoo, S., Parel, J., Manns, F. (2015). Calculation of ophthalmic viscoelastic device-induced focus shift during femtosecond laser-assisted cataract surgery. Investigative Ophthalmology and Visual Science, 56, 1222-1227. Maceo-Heilman, B., Manns, F., De Castro, A., Durkee, H., Arrieta, E., Marcos, S., Parel, J. (2015). Changes in monkey crystalline lens spherical aberration during simulated accommodation in a lens stretcher. Investigative Ophthalmology and Visual Science, 56, In Press (published online). Pour, H. M., Kanapathipillai, S., Zarrabi, K., Manns, F., Ho, A. (2015). Stretch-dependent changes in surface profiles of the human crystalline lens during accommodation: A finite-element study. Clinical and Experimental Optometry, 98, 126-137. Nankivil, D., Maceo, B., Durkee, H., Manns, F., Ehrmann, K., Kelly, S., Arrieta-Quintero, E., Parel, J. (2015). The zonules selectively alter the shape of the lens during accommodation based on the location of their anchorage points. Investigative Ophthalmology and Visual Science, 56, In Press (published online). Marussich, L., Manns, F., Nankivil, D., Maceo Heilman, B., Yao, Y., Arrieta-Quintero, E., Ho, A., Augusteyn, R., Parel, J. (2015). Measurement of crystalline lens volume during accommodation in a lens stretcher. Investigative Ophthalmology and Visual Science, 56, 4239-4248. Wang, S., Aglyamov, S., Karpiouk, A., Li, J., Emelianov, S., Manns, F., Lirin, K. (2013). Assessing the mechanical properties of tissue-mimicking phantoms at different depths as an approach to measure biomechanical gradient of crystalline lens. Biomedical Optics Express, 4(12), 2769-2780. deFreitas, C., Ruggeri, M., Manns, F., Ho, A., Parel, J. (2013). In vivo measurement of the average refractive index of the human crystalline lens using optical coherence tomography. Optics Letters, 38, 85-87. De Castro, A., Birkenfeld, J., Maceo, B., Arrieta, E., Manns, F., Parel, J., Marcos, S. (2013). Influence of shape and gradient refractive index in the accommodative changes of spherical aberration in non-human primate crystalline lenses. Investigative Ophthalmology and Visual Science, 54(9), 6197-6207. Siedlecki, D., de Castro, A., Gambra, E., Ortiz, S., Borja, D., Uhlhorn, S., Manns, F., Marcos, S., Parel, J. (2012). Distortion correction of OCT images of the crystalline lens: Gradient-Index approach. Optometry and Vision Science, 89, E709-E718. Hao, X., Jeffery, J., Le, T., McFarland, G., Johnson, G., Mulder, R., Garrett, Q., Manns, F., Nankivil, D., Arrieta, E., Ho, A., Parel, J., Hughes, T. (2012). High refractive index polysiloxane as injectable, in situ curable accommodating intraocular lens biomaterials. Biomaterials, 33, 5659-5671. Ruggeri, M., Uhlhorn, S., De Freitas, C., Ho, A., Manns, F., Parel, J. (2012). Imaging and full-length biometry of the eye during accommodation using Spectral-Domain OCT with an optical switch. Biomedical Optics Express, 3, 1506-1520. Augusteyn, R., Mohamed, A., Nankivil, D., Veerendranath, P., Arrieta, E., Taneja, M., Manns, F., Ho, A., Parel, J. (2011). Age-dependence of the optomechanical responses of ex vivo human lenses from India and the USA, and the force required to produce these in a lens stretcher: the similarity to in vivo disaccommodation. Vision Research, 51, 1667-1678. de Castro, A., Siedlecki, D., Borja, D., Uhlhorn, S., Parel, J., Manns, F., Marcos, S. (2011). Age-dependent variation of the Gradient Index profile in human crystalline lenses. Journal of Modern Optics, 58, 1781-1787. Maceo, B., Manns, F., Borja, D., Nankivil, D., Uhlhorn, S., Arrieta, E., Ho, A., Augusteyn, R., Parel, J. (2011). Contribution of the crystalline lens gradient refractive index to the accommodation amplitude in non?human primates: in vitro studies. Journal of Vision, 11, 13:23. Ale, J., Manns, F., Ho, A. (2011). Magnifications of single and dual element accommodative intraocular lenses: Paraxial optics analysis. Ophthalmic and Physiological Optics, 31, 7-16. Ale, J., Manns, F., Ho, A. (2011). Paraxial analysis of the depth-of-field of a pseudophakic eye implanted with Accommodating IOLs. Optometry and Vision Science, 88, 789-794. Chou, T., Kocaoglu, O., Borja, D., Ruggeri, M., Uhlhorn, S., Manns, F., Porciatti, V. (2011). Postnatal elongation of eye size in DBA/2J mice compared with C57BL/6J mice: In vivo analysis with whole-eye OCT. Investigative Ophthalmology and Visual Science, 52, 3604-3612. Ziebarth, N., Arrieta, E., Moy, V., Manns, F., Parel, J. (2011). Primate lens capsule elasticity assessed using Atomic Force Microscopy. Experimental Eye Research, 92, 490-494. Urs, R., Ho, A., Manns, F., Parel, J. (2010). Age-dependent Fourier model of the shape of the isolated ex vivo human crystalline lens. Vision Research, 50, In press. Borja, D., Siedlecki, D., De Castro, A., Uhlhorn, S., Ortiz, S., Arrieta, E., Parel, J., Marcos, S., Manns, F. (2010). Distortions of the posterior surface in optical coherence tomography images of the isolated crystalline lens: Effect of the lens index gradient. Biomedical Optics Express, 1, 1331-1340. Ale, J., Manns, F., Ho, A. (2010). Evaluation of the performance of accommodating IOL using paraxial optics analysis. Ophthalmic and Physiological Optics, 30, 132-142. Borja, D., Manns, F., Ho, A., Ziebarth, N., Acosta, A. C., Arrieta, E., Augusteyn, R. C., Parel, J. M. (2010). Optical power and biometric properties of the non-human primate isolated crystalline lens. Investigative Ophthalmology and Visual Science, 51, 2118-2125. Fedke, C., Manns, F., Ho, A. (2010). The entrance pupil of the human eye: a three-dimensional model as a function of viewing angle. Optics Express, 18, 22364-22376. Nankivil, D., Manns, F., Arrieta-Quintero, E., Ziebarth, N., Borja, D., Amelinckx, A., Bernal, A., Ho, A., Parel, J. M. (2009). Effect of anterior zonule transection on the change in lens diameter and power in cynomolgus monkeys during simulated accommodation. Investigative Ophthalmology and Visual Science, 50, 4017-4021.