Sarkar, Malancha - University of Miami

个人简介

Lecturer, Department of Biology, University of Miami, Coral Gables 2006 - Present Researcher, Miami Children Hospital, Miami, FL, USA 2006 Adjunct Faculty, Miami Dade College, Miami, FL, USA 2005 Senior Research Associate, 2001 - 2006 University of Miami Miller School of Medicine, Miami, FL, USA Researcher, Department of Veterinary Science, 1995 - 1996 National Institute of Health, Tokyo, Japan Ph.D. Zoology/Biochemistry, Banaras Hindu University, Varanasi, INDIA1995 M.Sc. Zoology Spl. Biochemistry, Banaras Hindu University, Varanasi, INDIA 1991 B.Sc. (Hon.) Zoology, Ranchi University, Ranchi, INDIA 1989

研究领域

My main focus is teaching but I do participate in research in my spare time. I am interested in understanding cancer drug resistance and also in development of new drugs from natural resources.

近期论文

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Subbarayan PR, Sarkar M, NagarajaRao S, Pilip S, Kumar P, Altman N, Reis I, Ahmed M, Ardalan B, Lokeshwar B. (2012), Achyranthes aspera (Apamarg) Leaf extract inhibits human pancreatic tumor growth in athymic mice by apoptosis, J. Ethnopharmacology 142, 523-30. Hammad H, Sarkar M, Subbarayan PR, Ardalan B. (2012), Thymidylate synthase 5' UTR polymorphic allele distribution in South Florida population. Journal of Cancer Therapy, (In Press). Hammad H, Sarkar M, Gupta N, Ardalan B,Subbarayan PR. (2012), The presence of three repeats in the 5’UTR region of Thymidylate synthase (TS) is associated with increased TS mRNA expression in culture human cell lines in vitro. Oncol Reports 27: 246-249 Subbarayan PR, Sarkar M, Impellizzeri S, Raymo F, Lokeshwar BL, Kumar P, Agarwal RP, Ardalan B. (2010), Anti-proliferative and Anticancer properties of Achyranthes aspera: Specific inhibitory activity against pancreatic cancer cells. Journal of Ethnopharmacolgy 13178-82 Subbarayan PR,Sarkar M,G.Nelson,Benitez E and Ardalan B (2010), Chronic exposure of colorectal cancer cells to fluoropyrimidine anlogues in vitro induces thymidylate syntahse and suppresses p53. A molecular explanation for the mechanism of 5-FU resistance. Anticancer research 30: 1149-1156. Sarkar M, Han T & Agarwal RP (2005), Arabinosylcytosine Mediated Reduction of Transcription Factor Sp1, and Down Regulation of Deoxycytidine Kinase in Arabinosylcytosine Resistant Human Lymphoid Cells, Biochem Pharmacol. 70(3):426-32