陈月琴 - 中山大学 - 生命科学学院

个人简介

教育经历： 1984年西北大学生物系理学学士； 1987年北京大学生物系理学硕士； 1996年中山大学生科院理学博士。工作经历： 2003年至今，聘为中山大学教授； 1999年，被聘为中山大学副教授； 1998-2005年先后在法国国家科研中心（CNRS），哈佛大学，美国陆军研究所任客座研究员。 1996-1998年，中山大学博士后。

研究领域

非编码RNA生物学

近期论文

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Huang W, Wang WT, Fang K, Chen ZH, Sun YM, Han C, Sun LY, Luo XQ, Chen YQ*. MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47. Mol Cancer. 2018 , 17:12. Sun LY, Li XJ, Sun YM, Huang W, Fang K, Han C, Chen ZH, Luo XQ, Chen YQ*, Wang WT*. LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1. Mol Cancer. 2018,17:127. Chen ZH, Wang WT, Huang W, Fang K, Sun YM , Liu SR,Luo XQ, Chen YQ*. The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway. Cell Death Differ. 2017,24: 212-24. Zhang JP, Yu Y, Feng YZ, Zhou YF, Zhang F, Yang YW, Lei MQ, Zhang YC, Chen YQ*. MiR408 Regulates Grain Yield and Photosynthesis via a Phytocyanin Protein. Plant Physiol. 2017 ,175:1175-85. Lin KY, Ye H, Han BW, Wang WT, Wei PP, He B Li XJ, Chen YQ*. Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma. Oncogene. 2016,35: 3376-86. Wang WT, Ye H, Wei PP, Han BW, He B, Chen ZH, Chen YQ*. LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner. J Hematol Oncol. 2016, 9:117. Zhang YC, Liao JY, Li ZY, Yu Y, Zhang JP, Li QF, Qu LH, Shu WS, Chen YQ*. Genome-wide screening and functional analysis identify a large number of long noncoding RNAs involved in the sexual reproduction of rice. Genome Biology. 2014,15:512. Zeng CW, Chen ZH, Zhang XJ, Han BW, Lin KY, Li XJ, Wei PP, Zhang H, Li YQ, Chen YQ*. MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy lysosomal pathway in acute promyelocytic leukemia. Autophagy. 2014,10, 1726–37. Fang K, Han BW, Chen ZH, Lin KY, Zeng CW, Li XJ,Li JH, Luo XQ, Chen YQ*. A distinct set of long non-coding RNAs in childhood MLL-rearranged acute lymphoblastic leukemia: biology and epigenetic target. Hum Mol Genet. 2014, 23: 3278-88. Wang, CY, Zhang SC, Yu Y, Luo YC, Liu Q Ju CL, Zhang YC, Qu LH, Lucas WJ, Wang XJ, Chen YQ*.MiR397b Regulates Both Lignin Content and Seed number in Arabidopsis via Modulating a Laccase Involved in Lignin Biosynthesis. Plant Biotech J. 2014, 12(8):1132-42. Wang WT, Zhao YN, Yan JX, Weng MY, Wang Y, Chen YQ*, Hong SJ. Differentially expressed microRNAs in the serum of cervical squamous cell carcinoma patients before and after surgery. J Hematol Oncol. 2014 Jan 10;7:6. Wang WT, Chen YQ*. Circulating miRNAs in cancer: from detection to therapy. J Hematol Oncol. 2014 ,5;7:86. Zhang YC, Yu Y, Wang CY, Li ZY, Liu Q, Xu J, Liao JY, Wang XJ, Qu LH, Chen F, Xin P, Yan C, Chu J, Li HQ, Chen YQ*.Overexpression of microRNA OsmiR397 improves rice yield by increasing grain size and promoting panicle branching. Nat Biotechnol. 2013, 31：848-53. Han BW, Chen YQ*. Potential Pathological and Functional Links Between Long Noncoding RNAs and Hematopoiesis. Sci. Signal. 2013, 6, re5. Wang WT, Zhao YN, Han BW, Hong SJ, Chen YQ*. Circulating microRNAs identified in a genome-wide serum microRNA expression analysis as noninvasive biomarkers for endometriosis.J Clin Endocrinol Metab. 2013, 98:281-9. Duan FT, Qian F, Fang K, Lin KY, Wang WT, Chen YQ*. miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression. Mol Cancer. 2013, 13;12:164.