Xie, Xiaohui - University of California, Irvine - Department of Developmental and Cell Biology

个人简介

Xiaohui Xie is a full profesor in the Department of Computer Science at UC Irvine, where he has been since 2007. He received his PhD from MIT, and completed his postdoctoral training at the Broad Institute of MIT and Harvard. He is interested in machine learning, bioinformatics, genomics, and neural computation. He lives in Irvine, California.

研究领域

Computational Biology, Bioinformatics, Genomics, Neural Computation, and Machine Learning

近期论文

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Daily K, Rigor P, Christley S, Xie X, Baldi P. (2010) Data structures and compression algorithms for high-throughput sequencing technologies.BMC Bioinformatics. 11:514. Wang Y, Christley S, Mjolsness E, Xie X. (2010) Parameter inference for discretely observed stochastic kinetic models using stochastic gradient descent.BMC Syst Biol. 4:99. Potkin SG, Macciardi F, Guffanti G, Fallon JH, Wang Q, Turner JA, Lakatos A, Miles MF, Lander A, Vawter MP, Xie X. (2010) Identifying gene regulatory networks in schizophrenia. Neuroimage. 53(3):839-47. Epub 2010 Jun 22. Chong HK, Infante AM, Seo YK, Jeon TI, Zhang Y, Edwards PA, Xie X, Osborne TF.(2010) Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1. Nucleic Acids Res38(18):6007-17. Epub 2010 May 18. Xie X. (2010) The Site-Frequency Spectrum of Linked Sites. Bull Math Biol [Epub ahead of print] Christley S, Nie Q, Xie X.(2009) Incorporating existing network information into gene network inference. PLoS One. 4(8):e6799. Seo YK, Chong HK, Infante AM, Im SS, Xie X, Osborne TF. (2009) Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif. Proc Natl Acad Sci U S A. 106(33):13765-9. Epub 2009 Aug 4. Xie X, Rigor P, Baldi P. (2009) MotifMap: a human genome-wide map of candidate regulatory motif sites. Bioinformatics. 25(2):167-74. Epub 2008 Nov 18.