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研究领域

Bioinformatics; Computational Biology – Dr. Baldi’s group works at the intersection of biological and computer sciences, using probabilistic/machine learning techniques to address biological problems and mine large data sets produced by massive data acquisition technologies, such as genome sequencing, high-throughput drug screening, and DNA microarrays. Current projects include the prediction of protein secondary and tertiary structure, the study of DNA structure in relation to several biological processes (protein binding, gene regulation, triplet repeat expansion diseases), and the analysis of gene expression data. Dr. Baldi’s group is building a suite of genomics and proteomics programs for the prediction of protein structure and function and the analysis of microarray data.

近期论文

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Whisenant TC, Ho DT, Benz RW, Rogers JS, Kaake RM, Gordon EA, Huang L, Baldi P, Bardwell L. (2010) Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors. PLoS Comput Biol. 6(8). pii: e1000908. Compani B, Su T, Chang I, Cheng J, Shah KH, Whisenant T, Dou Y, Bergmann A, Cheong R, Wold B, Bardwell L, Levchenko A, Baldi P, Mjolsness E. (2010) A Scalable and Integrative System for Pathway Bioinformatics and Systems Biology. Adv Exp Med Biol. 680:523-534. Cruz-Fisher MI, Cheng C, Sun G, Pal S, Teng A, Molina DM, Kayala MA, Vigil A,

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