Foley, Joe P. - Drexel University - Department of Chemistry

个人简介

National Research Council Postdoctoral Fellow, National Institute of Standards and Technology, 1983-85. Assistant Professor of Chemistry, Louisiana State University, 1985-91. Associate Professor of Chemistry, Louisiana State University, 1991. Associate Professor of Chemistry, Villanova University, 1991-97. Professor of Chemistry, Villanova University,1997-98. Professor of Chemistry, Drexel University, 1998 - present. Visiting Professor of Chemistry, University of Frankfurt (Germany), 2006-07.

研究领域

Separation science, especially the fundamentals and biomedical/pharmaceutical applications of the following voltage- or pressure-driven separation techniques: capillary electrophoresis, electrokinetic chromatography, capillary electrochromatography, and micellar liquid chromatography. Within these techniques, we explore novel separation modes and surfactant aggregate pseudophases (micelles, vesicles, microemulsions); chiral separations; and physicochemical measurements.

近期论文

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Freedman, K. J.; Haq, S. R.; Fletcher, M. R.; Foley, J. P.; Jemth, P.; Edel, J. B.; Kim, M. J. Nonequilibrium Capture Rates Induce Protein Accumulation and Enhanced Adsorption to Solid-State Nanopores. ACS Nano, 2014, 8, 12238-12249. DOI: 10.1021/nn5062645. Blackney, D. M.; Foley, J. P., Eliminating Biases in the Resolution and Analysis Time During the Simultaneous Determination of Anionic and Cationic Species in Capillary Zone Electrophoresis. LC-GC 2013, 31, 38-43. DePasquale, J.; White, N. J.; Ennis, E. J.; Zeller, M.; Foley, J. P.; Papish, E. T., Synthesis of chiral N-heterocyclic carbene (NHC) ligand precursors and formation of ruthenium(II) complexes for transfer hydrogenation catalysts. Polyhedron 2013, 58, 162-170. DOI: 10.1016/j.poly.2012.10.010. Zhang, J.; Burman, S.; Gunturi, S.; Foley, J. P. Method Development and Validation of Capillary Sodium Dodecyl Sulfate Gel Electrophoresis for the Characterization of a Monoclonal Antibody, J. Pharm. Biomed. Anal. 2010, 53, 1236-1243. Zhang, J.; Chakraborty, U.; Villalobos, A. P.; Brown, J. M.; Foley, J. P. Optimization and qualification of capillary zone electrophoresis method for glycoprotein isoform distribution of erythropoietin for quality control laboratory, J. Pharm. Biomed. Anal. 2009, 50, 538-543. Zhang, J.; Chakraborty, U.; Foley, J. P. Determination of residual cell culture media components by MEKC, Electrophoresis 2009, 30, 3971-3977. Kojtari, A. B.; Guetschow, E. D.; Foley, J. P. The effect of co-surfactant-modified micelles on chiral separations in EKC, Electrophoresis 2009, 30, 2829-2836. Kojtari, A.; Foley, J. P. Effect of Microemulsion Component Purity on the Chromatographic Figures of Merit in Chiral Microemulsion Electrokinetic Chromatography, J. Chromatogr. A., 2009, 1216, 3488-3491. (invited paper) Kahle, K. A.; Foley, J. P. “Chiral Microemulsion Electrokinetic Chromatography”, in Chiral Separations by Capillary Electrophoresis, Yvette Michotte and Ann Van Eeckhaut, Eds.; CRC Press, 2009, 235-270. Foley, J. P.; Hong, M.; Polinko, M. A.; Pascoe, R. J.; Ahuja, E. S. Compositional Effects on Electrophoretic and Chromatographic Figures of Merit in Electrokinetic Chromatography with Cetyltrimethylammonium Bromide/Sodium Octyl Sulfate Vesicles as the Pseudostationary Phase. Part 1: Effect of the Phase Ratio, Electrophoresis 2008, 29, 1180-1188. Kahle, K. A.; Foley, J. P. Influence of Microemulsion Chirality on Chromatographic Figures of Merit in Electrokinetic Chromatography: Results with Novel Three-Chiral-Component Microemulsions and Comparison with One- and Two-Chiral-Component Microemulsions. Electrophoresis, 2007, 28, 3024-3040. (invited paper) Kahle, K. A.; Foley, J. P. Review of Aqueous Chiral Electrokinetic Chromatography with an Emphasis on Chiral Microemulsion EKC. Electrophoresis, 2007, 28, 2503-2526. (invited review) Kahle, K. A.; Foley, J. P. Two-Chiral-Component Microemulsion Electrokinetic Chromatography—Chiral Surfactant and Chiral Oil: Part 2. Diethyl Tartrate. Electrophoresis, 2007, 28, 2644-2657. (invited paper) Weekley, B. S.; Foley, J. P. Dual-opposite-injection CZE: theoretical aspects and application to organic and pharmaceutical compounds, Electrophoresis 2007, 28, 697-711. (invited paper) Thomas, D. P.; Foley, J. P. Efficiency enhancements in micellar liquid chromatography through selection of stationary phase and alcohol modifier, J. Chromatogr. A 2007, 1149, 282-293. Kahle, K. A.; Foley, J. P. Two-chiral-component microemulsion electrokinetic chromatography-chiral surfactant and chiral oil: Part 1. Dibutyl tartrate, Electrophoresis 2007, 28, 1723-1734. Zhou, M. X.; Foley, J. P. Quantitative Theory of Electroosmotic Flow in Fused-Silica Capillaries Using an Extended Site-Dissociation-Site-Binding Model, Anal. Chem. 2006, 78, 1849-1858. Pascoe, R. J.; Masucci, J. A.; Foley, J. P. Investigation of vesicle electrokinetic chromatography as an in vitro assay for the estimation of intestinal permeability of pharmaceutical drug candidates, Electrophoresis 2006, 27, 793-804. Kahle, K. A.; Foley, J. P. Chiral microemulsion electrokinetic chromatography: effect of cosurfactant identity on enantioselectivity, methylene selectivity, resolution, and other chromatographic figures of merit, Electrophoresis 2006, 27, 4321-4333. Kahle, K. A.; Foley, J. P. Chiral microemulsion electrokinetic chromatography with two chiral components: improved separations via synergies between a chiral surfactant and a chiral cosurfactant, Electrophoresis 2006, 27, 896-904.