Zhang, Jin - University of Western Ontario - Department of Chemical and Biochemical Engineering

个人简介

Dr. Zhang’s expertise and research interests include the design, processing, surface modification, and characterization of nanocomposites for the applications in the fields of bioengineering and sustainable energy. The goal of the Multifunctional Nanocomposites Lab (MNL) led by Dr. Zhang at Western is to develop multifunctional nanomaterials used for advanced biomedical devices. To achieve the goal, the Zhang group is dedicated to the study on the surface and interface of hybrid nanomaterials, and the interaction between nanomaterials and biological systems. Currently, the research activities of the Zhang group focus on developing advanced nanomaterials with enhanced chemical, magnetic, and optical properties. Three research directions in the Zhang group include (1) multifunctional nanocomposites-processing & properties, (2) targeted drug delivery, and (3) protein and chemical sensor. Recently, Zhang is rewarded by the Grand Challenges Canada-Canadian Rising Stars in Global Health for her research work on "Non-invasive Diagnostic Tool for Diabetes". Dr. Zhang holds cross appointments with the Department of Ophthalmology, Biomedical Engineering, and Medical Biophysics, at Western.

研究领域

Development of top-down and bottom-up processes for the synthesis of new materials at nano-scale Laser-assisted process for hybrid nanocomposites film deposition Wet chemical reaction Multifunctional nanocomposite-based protein and chemical sensors The biocompatible nanocomposite-based contact lens sensor has been attracting worldwide media attention; Nanotechnology Now PRESSTV The Institute of Nanotechnology (IoN) Multifunctional nanoparticles used for the bioengineering e.g. targeted drug delivery, etc. Self-assembling 2-D array of nanoparticles ( Jin Zhang, et al., “Design of Nanopaticles as Drug Carrier for Cancer Therapy”. Cancer, Genomics & Proteomics, 3, 147, (2006)). Magnetic core-optical shell (Jin Zhang, et al., "Iron Nanoparticles with Au Coated Superparamagnetic Nanoparticles”, Journal of Physical Chemistry B, 110, 7122, (2006)). Optical nanocolloids (Jin Zhang, et al., Journal of Physical Chemistry B, 107; 6920, (2003)).

近期论文

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Guobang Huang, Yi Chen, and Jin Zhang*. "Nanocomposited Coatings Produced by Laser-assisted Process to Prevent Silicone Hydogels from Protein Fouling and Bacterial Contamination”. Applied Surface Science. (2015). 10.1016/j.apsusc.2015.10.185 Longyan Chen, Yige Bao, John Denstedt, Jin Zhang*. "Nanostructured Bioluminescent Sensor for Rapidly Detecting Thrombin". Biosensors and Bioelectronics. (2015). DOI: 10.1016/j.bios.2015.09.010 Yi Chen, Longyi Chen, Longyan Chen, and Jin Zhang*, "Deposition of ZnO Nanocrystals on Fe3O4 Nanocubes and Their Special Luminescent and Magnetic Properties". Particle & Particle Systems Characterization. (2015). DOI: 10.1002/ppsc.201500053 Pei Yin, Guobang Huang, Wai Hei Tse, Yige Bao, John Denstedt, and Jin Zhang*, "Laser-assisted Surface Modification of Nanocomposited Silicone Hydrogels for Inhibiting the Growth of Biofilm”, Journal of Materials Chemistry B. (2015) DOI: 10.1039/C4T B01871K. Yi Chen, Wai Hei Tse, Longyan Chen, and Jin Zhang*, “Ag Nanoparticles-decorated ZnO Nanorod Array on a Mechanical Flexible Substrate with Enhanced Optical and Antimicrobial Properties”, Nanoscale Research Letters. 10:106 (2015). DOI: 10.1186/s11671-014-0712-3. Yi Chen, Xiaoxuan Guo, Wai Hei Tse, Tsun-Kong Sham, and Jin Zhang*,"Magnetic Anisotropy Induced in NiCo Granular Nanostructures By ZnO Nanorods Deposited on a Polymer Substrate”. RSC Advances. 4 (89), 47987 - 47991, (2014). DOI: 10.1039/C4RA07210C Jin Zhang* Longyan, Chen, Wai Hei Tse, Robert Bi, Longyi Chen, “Protein-conjugated Nanoparticles used for Biomedical Devices” IEEE Nano-mag. (2014) (invited). Longyan Chen, Alex Siemiarczuk, Hong Hai, Yi Chen, and Jin Zhang*, “Development of Biocompatible and Proton-resistant Quantum Dots Assembled on Gelatin Nanospheres”, Langmuir, 30 (7), pp 1893–1899 (2014). DOI: 10.1021/la403914k Jin Zhang*, Robert Bi, William Hodge, Pei Yin, Wai Hei Tse, “Nanocomposite-based Contact Lens for Delivery of Hydrophilic Protein Drug”, Journal of Materials Chemistry B. 1, 4388-4395, (2013) DOI: 10.1039/C3TB20391C. Longyan Chen, Fereidoon S. Razavi, Abdul Mumin, Xiaoxuan Guo, Tsun-Kong Sham, and Jin Zhang*, “Multifunctional Nano particles for Rapid Bacterial Capture, Detection, and Decontamination” RSC Advances. 3, 2390-2397 (2013). DOI: 10.1039/C2RA22286H Jin Zhang*, Xianbin Wang, Longyan Chen, Jiaxin Li, and Kevin Luzak, “Harnessing a Nanostructured Fluorescence Energy Transfer Sensor for Quick Detection of Extremely Small Amounts of Glucose”, J. Diabetes Sci. Tech. 7(1):45–52, (2013). (invited) Longyan Chen, Adrienne Willoughby, and Jin Zhang*, “Luminescent Gelatin Nanospheres by Encapsulating CdSe Quantum Dots”, Luminescence-the Journal of Biological and Chemical Luminescence, 2014; 29: 74–78. Longyan Chen and Jin Zhang*, “Bioconjugated Magnetic Nanoparticles for Rapid Capture of Gram-positive Bacteria”, J. Biosensor & Bioelectronics. S11:005. (2012). Farida Akhter, Jesse Zhu, Jin Zhang*, “Nanoencapsulation of Protein Drug for Controlled Release”. J Physic Chem Biophysic. S11-001 (2012). Drew Kuraitis, Zahra Arzhangi, Alex J. Hyatt, Branka Vulesevic, Kimberley Merrett, Jin Zhang, Erik J. Suuronen, and May Griffith, “Tertiary Biomaterial Encapsulation Controls the Release of FGF-2 without Impacting Bioactivity”, The Open Tissue Engineering and Regenerative Medicine Journal, 5, 43-49 (2012). Longyan Chen and Jin Zhang*, “Development of Hydrophilic Iron Oxide Nanocubes”, Sci. Adv. Mater., 4, 859-862 (2012). Taylor Davis, Jin Zhang, Jose E. Herrera, “Surfactant assisted incorporation of single walled carbon nanotubes into a chitosan-PVP polymer”, J Nanoeng. & Nanomanufacturing, 1, 320-324 (2011). Jin Zhang* and Longyan Chen, “NiCo films with perpendicular magnetization anisotropy deposited on dielectric substrate by using polyol process”, Mater. Lett.. 65, 19-20 Pages 2944-2946 (2011). Drew Kuraitis, Pingchuan Zhang, Kimberley McEwan, Yan Zhang, Tanja Sonfrenovic, Daniel McKee, Jin Zhang, May Griffith, Xudong Cao, Marc Ruel, Erik J Suuronen, “A stromal cell-derived factor-1 releasing matrix enhances Progenitor Cell Response in Ischemia”. J. Eur. Cells & Mater., 22, 109-116, (2011). Jin Zhang*, William Hodge, Cindy Hutnick, and Xianbin Wang, “Non-invasive diagnostic technology for diabetes through monitoring ocular glucose”, J. Diabetes Sci. Tech. 5,166, (2011). (invited) Abdul M. Mumin, John W. Barrett, Gregory A. Dekaban, and Jin Zhang*, “Dendritic Cell Internalization of Fluorescent Mesoporous Silica Nanoparticles”, J. Colloid Interface Sci., 353 (1), 156-162, (2011). Jin Zhang*, Jiaxin Li, Fereidoon S. Razavi, and Abdul Md. Mumin, “One-pot Synthesis and Characterization of Rhodamine Derivative-loaded Magnetic Core-shell Nanoparticles”, J. Nanoparticles Res., 13, 1909–1916, (2011). Bettina Bareiss, Masoud Ghorbani, Fengfu Li, Jessie A. Blake, Juan C. Scaiano, Jin Zhang, Chao Deng, Kimberley Merrett, James Harden, Francisco Diaz-Mitoma, and May Griffith, “Controlled Release of Acyclovir Through Bioengineered Corneal Implants with Silica Nanoparticle Carriers”, the Open Tissue Eng. & Reg. Med., 3, 10. (2010). Jin Zhang*, Lynne-Marie Postovit, Dashan Wang, Richard B. Gardiner, Richard Harris, Abdul M. Mumin, and Anu A. Thomas, “In situ loading of Basic Fibroblast Growth Factor (bFGF) within Porous Silica Nanoparticles for a Prolonged Release”, Nanoscale Res. Lett., 4, 1297-1301, (2009).