当前位置: X-MOL首页全球导师 海外导师 › KOH, Ming Joo
扫描左侧二维码
使用公众号菜单
手机上轻松查询100,000+导师

个人简介

NUS Inauguration Grant, NUS, 2019 President's Assistant Professorship, NUS, 2018 Bristol-Myers Squibb Graduate Fellowship in Synthetic Organic Chemistry, 2016-2017 LaMattina Family Graduate Fellowship in Chemical Synthesis, 2016 Best Poster Award, ISOM XXI, 2015

研究领域

The key objective of our program is to develop sustainable and enabling catalytic solutions that address critical and unresolved problems in chemical synthesis. Our research approach will leverage creative, direct and unprecedented disconnections of complex target molecules to fuel our efforts in devising practical stereoselective methods that utilize abundant, biocompatible and inexpensive catalysts. Insights gained from mechanistic studies will aid us in designing new catalyst systems that promote transformations to facilitate economically and environmentally viable preparation of important compounds for the chemical, pharmaceutical and polymer industries. Current topics of interest include homogeneous base metal catalysis, heterogeneous single-atom catalysis and radical chemistry.

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Liu, C.; Chen, Z.; Yan, H.; Yam, K. M.; Gao, J.; Du, Y.; Xi, S.; Li, J.; Zhao, X.; Xu, H.; Li, X.; Fu, W.; Leng, K.; Xie, K.; Pennycook, S. J.; Liu, B.; Zhang, C.; Koh, M. J.; Loh, K. P., Expedient Synthesis of E-Hydrazone Esters and 1H-Indazole Scaffolds through Heterogeneous Single-Atom Platinum Catalysis. Sci. Adv. 2019, in press. Mu, Y.; Nguyen, T. T.; Koh, M. J.; Schrock, R. R.; Hoveyda, A. H., E- and Z-, Di-,and Trisubstituted Alkenyl Nitriles through Catalytic Cross-Metathesis. Nat. Chem. 2019, 11, 478-487. Nguyen, T. T.*; Koh, M. J.*; Mann, T. J.; Schrock, R. R.; Hoveyda, A. H. “Synthesis of E- or Z-Trisubstituted Alkenes by Catalytic Cross-Metathesis” Nature, 2017, 552, 347. (*these authors contributed equally). Nguyen, T. T.; Koh, M. J.; Mann, T. J.; Schrock, R. R.; Hoveyda, A. H. Synthesis of E- or Z-Trisubstituted Alkenes by Catalytic Cross-Metathesis. Nature 2017, 552, 347-354. Koh, M. J.; Nguyen, T. T.; Lam, J. K.; Torker, S.; Hyvl, J.; Schrock, R. R.; Hoveyda, A. H. Molybdenum Chloride Catalysts for Z-Selective Olefin Metathesis Reactions. Nature 2017, 542, 80-85. Shen, X.; Nguyen, T. T.; Koh, M. J.; Xu, D.; Speed, A.W. H.; Schrock, R. R.; Hoveyda, A. H. Kinetically E-Selective Macrocyclic Ring-Closing Metathesis. Nature 2017, 541, 380. Torker, S.; Koh, M. J.; Khan, R. K. M.; Hoveyda, A. H. “Regarding a Persisting Puzzle in Olefin Metathesis with Ru Complexes: Why are Transformations of Alkenes with a Small Substituent Z-selective?” Organometallics, 2016, 35, 543. Nguyen, T. T.; Koh, M. J.; Shen, X.; Romiti, F.; Schrock, R. R.; Hoveyda, A. H. Kinetically Controlled E-Selective Catalytic Olefin Metathesis. Science 2016, 352, 569-575. Koh, M. J.; Nguyen, T. T.; Zhang, H.; Schrock, R. R.; Hoveyda, A. H. Direct Synthesis of Z-Alkenyl Halides by Catalytic Cross-Metathesis. Nature 2016, 531, 459-465. Koh, M. J.; Khan, R. K. M.; Torker, S.; Yu, M.; Mikus, M. S.; Hoveyda, A. H. High-Value Alcohols and Higher-Oxidation-State Compounds by Catalytic Z-Selective Cross-Metathesis. Nature 2015, 517, 181-186. Koh, M. J.; Khan, R. K. M.; Torker, S.; Hoveyda, A. H. “Broadly Applicable Z- and Diastereoselective Ring-Opening/Cross-Metathesis Catalyzed by a Dithiolate Ru Complex” Angew. Chem. Int. Ed., 2014, 53, 1968. Teo, W.; Rao, W.; Koh, M. J.; Chan, P. W. H. “Gold-Catalyzed Domino Aminocyclization/1,3-Sulfonyl Migration of N-Substituted-N-Sulfonyl-aminobut-3-yn-2-ols to 1-Substituted-3-Sulfonyl-1H-pyrroles” J. Org. Chem., 2013, 78, 7508. Rao, W.; Koh, M. J.*; Li, D.*; Hirao, H.; Chan, P. W. H. “Gold-Catalyzed Cycloisomerization of 1,6-Diyne Carbonates and Esters to 2,4a-Dihydro-1H-fluorenes” J. Am. Chem. Soc., 2013, 135, 7926. (*these authors contributed equally). Rao, W.; S.; Koh, M. J.; Chan, P. W. H. “Gold-Catalyzed Cycloisomerization of 1,7-Enyne Esters to Structurally Diverse cis-1,2,3,6-Tetrahydropyridin-4-yl Ketones” J. Org. Chem., 2013, 78, 3183. Sze, E. M. L.; Koh, M. J.*; Tjia, Y. M.*; Rao, W.; Chan, P. W. H. “Synthesis of (Z)-1,2-Dihydro-1-tosylbenzo[b]azepin-3-ones by Two-step, One-Pot Gold-Catalyzed Tandem Heterocyclization/Petasis-Ferrier Rearrangement of 2-(N-(Prop-2-ynyl)-N-tosylamino)benzaldehydes” Tetrahedron, 2013, 69, 7471. (*these authors contributed equally). (highlighted by SYNFACTS, Synfacts, 2013, 9, 945). Rao, W.; Koh, M. J.; Kothandaraman, P.; Chan, P. W. H. “Gold-Catalyzed Cycloisomerization of 1,7-Diyne Benzoates to Indeno[1,2-c]azepines and Azabicyclo[4.2.0]octa-1(8),5-dines” J. Am. Chem. Soc. 2012, 134, 10811. (highlighted by SYNFACTS, Synfacts, 2012, 9, 952).

推荐链接
down
wechat
bug