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Mechanism of chromosome segregation using molecular biology and genomic tools. Analysis of yeast stress response during fermentation using genomics approach.

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Anderson, M.J., Barker, S.L., Boone, C. and Measday, V. (2011) “Identification of RCN1 and RSA3 as ethanol tolerant genes in Saccharomyces cerevisiae using a high copy barcoded library” FEMS Yeast Research Nov 12 Fang, N.N., Ng, A.H.M., Measday, V. and Mayor, T. (2011) Nature Cell Biology Oct 9; 13(11): 1344-52 Piggott, N., Cook, M., Tyers, M. and Measday, V. (2011) “Genome-wide fitness profiles reveal a requirement for autophagy during yeast fermentation” G3: Genes, Genomes, Genetics 1: 353-367 (journal cover image from our paper, new journal) Walkey, C.J., Luo, Z., Borcher, C.H., Measday, V. and van Vuuren, H.J. (2011) “The Saccharomyces cerevisiae fermentation stress response protein Igd1/Yfr017p regulates glycogen levels by inhibiting the glycogen debranching enzyme” FEMS Yeast Research 11(6): 499-508 Ma, L., McQueen, J., Cuschieri, L., Vogel, J. and Measday, V. (2007) “Spc24 and Stu2 promote spindle integrity when DNA replication is stalled” Molecular Biology of the Cell 18(8): 2805-2816 Baetz, K., Measday, V. and Andrews, B. (2006) “Revealing Hidden Relationships Among Yeast Genes Involved in Chromosome Segregation Using Systematic Synthetic Lethal and Synthetic Dosage Lethal Screens” Cell Cycle Vol. 5, Issue 6: 592-595 Monpetit, B., Thorne, K., Barrett, I., Andrews, K., Jadusingh, R., Hieter, P. and Measday, V. (2005) “Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae” Genetics 171: 1-13. Measday, V#., Baetz, K#., Guzzo, J., Yuen, K., Kwok, T., Sheikh, B., Ding, H., Ueta, R., Hoac, T., Cheng, B., Pot, I., Tong, A., Yamaguchi-Iwai, Y., Boone, C. Hieter, P. and Andrews, B. (2005) “Systematic yeast synthetic lethal and synthetic dosage lethality screens identify genes required for chromosome segregation” Proceedings of the National Academy of Sciences USA 102(39): 13956-13961. #authors contributed equally Measday, V. and Hieter, P. (2004) “Kinetochore substructure comes to MIND” Nature Cell Biology 6(2): 94-95. Pot, I., Measday, V., Snydsman, B., Cagney, G., Fields, S., Davis, T.N., Muller, E.G.D. and Hieter, P. (2003) “Chl4p and Iml3p are two new members of the budding yeast outer kinetochore” Molecular Biology of the Cell 14(2): 460-476. Measday, V., Hailey, D.W., Pot, I., Givan, S., Hyland, K.M. Cagney, G., Fields, S., Davis, T.N. and Hieter, P. (2002) “Ctf3p, the Mis6 budding yeast homologue, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore” Genes & Development 16(1): 101-113. Measday, V. and Hieter, P. (2002) “Synthetic Dosage Lethality” Guide to Yeast Genetics and Molecular and Cell Biology, Parts B and C. Methods in Enzymology 350: 316-326. McBride, H.J., Sil, A., Measday, V., Yu, Y., Moffat, J., Maxon, M.E., Herskowitz, I., Andrews, B. and Stillman, D. (2001) “The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae” Molecular Microbiology 42(2): 345-353. Macpherson, N., Measday, V., Moore L. and Andrews, B. (2000) “A yeast taf17 mutant requires the Swi6 transcriptional activator for viability and shows defects in cell cycle-regulated transcription” Genetics 154(4): 1561-1576. Measday, V., McBride, H., Moffat J., Stillman D. and Andrews, B. (2000) “Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast” Molecular Microbiology 35(4): 825-834. Andrews, B. and Measday, V. (1998) “The cyclin family of budding yeast: abundant use of a good idea. Trends in Genetics” 14(2): 66-72. Measday, V., Moore, L., Retnakaran, R., Lee, J., Donoviel, M., Neiman A. M. and Andrews, B. (1997) “A Family of Cyclin-Like Proteins that Interact with the Pho85 Cyclin-Dependent Kinase” Molecular and Cellular Biology 17(3): 1212-1223. Ellis, C., Measday, V. and Moran, M.F. (1995) “Phosphorylation-dependent complexes of p120 Ras-specific GTPase-activating protein with p62 and p190” Methods in Enzymology 255: 179-192. Measday, V., Moore, L., Ogas, J., Tyers, M. and Andrews, B. (1994) “The Pcl2 (OrfD)-Pho85 Cyclin-Dependent Kinase Complex, a Cell Cycle Regulator in Yeast” Science 266: 1391-1395.

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