个人简介

B.Sc. (Chemical Physics), M.Sc. (Chemistry), Ph.D. (Chemistry)

研究领域

Intracellular transport, Developmental modeling, Pattern formation, Model reduction, Transcription, Stochastic kinetics

The work of my group lies at the interface between chemistry, biology and mathematics, with occasional excursions into physics. We use a combination of mathematical reasoning and computer simulation to try to understand a variety of phenomena, with a particular emphasis on biological and chemical systems. Along the way, we have the opportunity to study mathematical problems such as the relationship between delay and ordinary differential equations.

近期论文

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Blessing E. Okeke and Marc R. Roussel (2015) An invariant-manifold approach to lumping. Math. Model. Nat. Phenom. 10, 149–167. [Invited paper for a special issue dedicated to Alexander Gorban] Md. Ruhul Amin and Marc R. Roussel (2014) Graph-theoretic analysis of a model for the coupling between photosynthesis and photorespiration. Can. J. Chem. 92, 85–93. [Special issue dedicated to Paul Brumer] Marc R. Roussel (2013) On the distribution of transcription times. Biomath 2, 1307247:1–14. [Invited paper associated with Biomath 2013] Abir U. Igamberdiev and Marc R. Roussel (2012) Feedforward non-Michaelis-Menten mechanism for CO2 uptake by Rubisco: Contribution of carbonic anhydrases and photorespiration to optimization of photosynthetic carbon assimilation. BioSystems 107, 158–166. Marc R. Roussel and Martin J. Slingerland (2012) A biochemically semi-detailed model of auxin-mediated vein formation in plant leaves. BioSystems 109, 475–487. [Invited paper for a special issue on Biological Morphogenesis] Marc R. Roussel (2012) Further studies of the functional equation truncation approximation. Can. Appl. Math. Q. 20, 209–227. [Special issue dedicated to Herb Friedman] Marc R. Roussel and Terry Tang (2012) Simulation of mRNA diffusion in the nuclear environment. IET Syst. Biol. 6, 125–133. [Invited paper for a special issue on ``Modelling noise in biochemical reaction networks''] Maya Mincheva and Marc R. Roussel (2012) Turing-Hopf instability in biochemical reaction networks arising from pairs of subnetworks. Math. Biosci. 240, 1–11. Marc R. Roussel and Abir U. Igamberdiev (2011) Dynamics and mechanisms of oscillatory photosynthesis. Biosystems 103, 230–238. [Special issue on Computational Models of Photosynthesis] Taunia L. L. Closson and Marc R. Roussel (2009) The flattening phase transition in systems of trapped ions. Can. J. Chem. 87, 1425–1435. [Invited paper for a special issue dedicated to Professor Tom Ziegler] Miguel A. Aon, Marc R. Roussel, Sonia Cortassa, Brian O'Rourke, Douglas B. Murray, Manfred Beckmann and David Lloyd (2008) The scale-free dynamics of eukaryotic cells. PLoS ONE 3, e3624:1–12. Marc R. Roussel and David Lloyd (2007) Detection of a chaotic metabolic attractor by real-time monitoring of a multi-oscillatory state in a yeast continuous culture. FEBS J. 274, 1011–1018. Maya Mincheva and Marc R. Roussel (2007) Graph-theoretic methods for the analysis of chemical and biochemical networks. I. Multistability and oscillations in ordinary differential equation models. J. Math. Biol. 55, 61–86. Maya Mincheva and Marc R. Roussel (2007) Graph-theoretic methods for the analysis of chemical and biochemical networks. II. Oscillations in networks with delays. J. Math. Biol. 55, 87–104. Marc R. Roussel, Alexander A. Ivlev and Abir U. Igamberdiev (2007) Oscillations of the internal CO2 concentration in tobacco leaves transferred to low CO2. J. Plant Physiol. 164, 1188–1196. Marc R. Roussel and Rui Zhu (2006) Stochastic kinetics description of a simple transcription model. Bull. Math. Biol. 68, 1681–1713. Santiago Schnell, Michael J. Chappell, Neil D. Evans and Marc R. Roussel (2006) The mechanism distinguishability problem in biochemical kinetics: The single-enzyme single-substrate reaction as a case study. C. R. Biologies 329, 51–61. Kevin L. Davis and Marc R. Roussel (2006) Optimal observability of sustained stochastic competitive inhibition oscillations at organellar volumes. FEBS J. 273, 84–95. Maya Mincheva and Marc R. Roussel (2006) A graph-theoretic method for detecting potential Turing bifurcations. J. Chem. Phys. 125, 204102:1–8. Included in the Dec. 1, 2006 issue of the compilation Virtual Journal of Biological Physics Research. Marc R. Roussel and Terry Tang (2006) The functional equation truncation method for approximating slow invariant manifolds: A rapid method for computing intrinsic low-dimensional manifolds. J. Chem. Phys. 125, 214103:1–7.