B. Sc. (Zhengzhou University, 1983)
M.S. (Chinese Academy of Sciences, 1988)
Ph. D. (McGill University, 1992)
NSERC Postdoctoral Fellow (Stanford University, 1992-94)
Visiting Faculty, UC Berkeley (2002)
Professor (Assistant, Associate, Full) (Tulane University, 1994-2003)
(US) NSF CAREER Award, 1998-2002
Outstanding Young Oversea Scientist Award (NSFC), 2001
(US) Presidential Green Chemistry Challenge Award (Academic), 2001
Japan Society for Promotion of Science (Senior) Fellow, 2002
Honorary Research Professor (Chemistry Institute, Chinese Academy of Science)
Canadian Green Chemistry and Engineering Award (individual), 2010
Award of Merit, Federation of the Chinese Canadian Professionals (ont), 2011
R. U. Lemieux Award (CSC), 2015
Alfred Bader Award (CSC), 2018
1. Green Chemistry:
Explore new catalytic reactions that have high atom-efficiency in water and other cleaner media (CO2 and Ionic Liquids), and to transform these reactions into general synthetic tools for synthesizing biologically important compounds and organic materials in a cost-effective and environmentally friendly manner.
C-C bond formations via catalytic C-H and C-X activation
Catalytic cyclization reactions
Catalytic asymmetric reactions
Catalytic functionalization of renewable materials.
2. Synthesis of biologically active compounds:
Developing new methods for synthesizing natural products and other biologically important compounds. One special interest is to develop synthesis and study of "Chemical Sensitizers" for targeted cancer therapy.
Catalyst-Free and Redox-Neutral Innate Trifluoromethylation and Alkylation of Aromatics Enabled by Light Journal of the American Chemical Society Peng Liu, Wenbo Liu, Chao-Jun Li
Formal aromaticity transfer for palladium-catalyzed coupling between phenols and pyrrolidines/indolines Chemical Science Zihang Qiu, Jiang-Sheng Li and Chao-Jun Li
Carbonyls as Latent Alkyl Carbanions for Conjugate AdditionsAngewandte Chemie International Edition Xi-Jie Dai, Haining Wang, Chao-Jun Li
Umpolung Addition of Aldehydes to Aryl IminesAngewandte Chemie International EditionNing Chen, Xi-Jie Dai, Haining Wang and Chao-Jun Li
Aldehydes as alkyl carbanion equivalents for additions to carbonyl compoundsNature Chemistry Haining Wang*, Xi-Jie Dai*, Chao-Jun Li
Photo-induced Metal-Catalyst-Free Aromatic Finkelstein ReactionJournal of American Chemical Society Lu Li, Wenbo Liu, Huiying Zeng, Xiaoyue Mu, Gonzalo Cosa, Zetian Mi, and Chao-Jun Li
Catalytic Fehling's Reaction: An Efficient Aerobic Oxidation of Aldehyde Catalyzed by Copper in Water Angewandte Chemie International EditionLiu, M.; Li, C.-J.
Photo-induced iodination of aryl halides under very mild conditions Nature ProtocolsLi, L.; Liu, W.; Mu, X.; Mi, Z.; Li, C.-J.
Li, L.; Mu, X.; Liu, W.; Wang, Y.; Mi, Z.; Li, C.-J. "Simple and Clean Photoinduced Aromatic Trifluoromethylation Reaction" J. Am. Chem. Soc. 2016, 138, 5809
Dai, X.-J.; Li, C.-J. "En Route to A Practical Primary Alcohol Deoxygenation" J. Am. Chem. Soc. 2016, 138, 5433
Chen, Z.; Zeng, H.; Girard, S. A.; Wang, F.; Chen, N.; Li, C.-J. Formal Direct Cross-Coupling of Phenols with Amines. Angew. Chem,. Int. Ed. 2015, 54, 14487. This publication was feaured by "Chem. Eng. News"
Querard, P.; Girard, S. A.; Uhlig, N.; Li, C.-J. Gold-catalyzed tandem reactions of amide-aldehyde-alkyne coupling and cyclization-synthesis of 2,4,5-trisubstituted oxazoles. Chem. Sci. 2015, 6, 7332.
Chen, Z.; Zeng, H.; Gong, H.; Wang, H.; Li, C.-J. Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines. Chem. Sci. 2015, 6, 4174.
Liu, M.; Wang, H.; Zeng, H.; Li, C.-J. Silver(I) as a widely applicable, homogeneous catalyst for aerobic oxidation of aldehydes toward carboxylic acids in water—“silver mirror”: From stoichiometric to catalytic. Sci. Adv. 2015, 1. e1500020.
Li, L.; Liu, W.; Zeng, H.; Mu, X.; Cosa, G.; Mi, Z.; Li, C.-J. Photo-induced Metal-Catalyst-Free Aromatic Finkelstein Reaction J. Am. Chem. Soc. 2015, 137, 8328.
Li, L.; Mu, X.; Liu, W.; Mi, Z.; Li, C.-J. Simple and Efficient System for Combined Solar Energy Harvesting and Reversible Hydrogen Storage J. Am. Chem. Soc. 2015, 137, 7576.
Liu, W.; Li, L.; Li, C.-J. Empowering a transition-metal-free coupling between alkyne and alkyl iodide with light in water Nat. Commun. 2015, 6, 6526.
Gong, H.; Zeng, H.; Zhou, F.; Li, C.-J. Rhodium(I)-Catalyzed Regiospecific Dimerization of Aromatic Acids: Two Direct C-H Bond Activations in Water Angew. Chem,. Int. Ed. 2015, 54, 5718.
Girard, S. A.; Knauber, T.; Li, C.-J. The Cross-Dehydrogenative Coupling of Csp3-H Bonds:
A Versatile Strategy for C-C Bond Formations Angew. Chem,. Int. Ed. 2014, 53, 74.
Li, L.; Mu, X.; Liu, W.; Kong, X.; Fan, S.; Mi, Z.; Li, C.-J. Thermal Non-Oxidative Aromatization of Light Alkanes Catalyzed by Gallium Nitride Angew. Chem,. Int. Ed. 2014, 53, 14106.
Zeng, H.; Li, C.-J. A Complete Switch of the Directional Selectivity in the Annulation of 2-Hydroxybenzaldehydes with Alkynes Angew. Chem,. Int. Ed. 2014, 53, 13862.
Sharma, A.; Mejía, D.; Regnaud, A.; Uhlig, N.; Li, C.-J.; Maysinger, D.; Kakkar, A. Combined A3 Coupling and Click Chemistry Approach for the Synthesis of Dendrimer-Based Biological Tools ACS Macro Lett. 2014, 3, 1079.
Uhlig, N.; Li, C.-J. Aniline Carbamates: A Versatile and Removable Motif for Palladium-Catalyzed Directed C-H Activation Chem. Eur. J. 2014, 20, 12066.
Zhou, F.; Li, C.-J. The Barbier-Grignard-type Arylation of Aldehydes Using Unactivated Aryl Iodides in Water" Nat. Commun. 2014, 5, 4254. This publication was feaured by "Chem. Eng. News", "Sciencedaily", "Chemical Processing" and on the McGill homepage.
Li, L.; Fan, S.; Mu, X.; Mi, Z.; Li, C.-J. Photoinduced Conversion of Methane into Benzene over GaN Nanowires. J. Am. Chem. Soc. 2014, 136, 7793-7796. This publication was feaured by Chem. Eng. News