个人简介
教育及科研工作背景:
2019- 中国海洋大学,教授
2016-2018 哈佛大学医学院, Instructor in Medicine
2016-2018 麻省总医院, Assistant Biologist
2009-2016 麻省总医院 / 哈佛大学医学院, 博士后
2004-2009 清华大学, 博士
研究领域
A. 胚胎器官发生
B. 成体器官(心脏)再生
C. 极端环境海洋生物抗性的分子机制
近期论文
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1. Lan W, Liu S, Zhao L* , Su Y*. (2020) Regulation of Drosophila hematopoiesis
in lymph gland: from a developmental signaling point of view. International
Journal of Molecular Sciences 21(15): 5246.
2. Wang L, Yang J, Wang H, Ran C, Su Y, Zhao L* . (2019) A highly selective
turn-on fluorescent probe for the detection of Aluminum and its application to
bio-imaging. Sensors 19(11): 2423.
3. Chi C, Wang L, Lan W, Zhao L* , Su Y * . (2018) PpV, acting via the JNK
pathway, represses apoptosis during normal development of Drosophila wing.
Apoptosis 23:554-562.
4. Zhao L , Wang L, Chi C, Lan W, Su Y*. (2017) The emerging roles of
phosphatases in Hedgehog pathway. Cell Communication and Signaling 15:35 -45 .
5. Zhao L , Ben-Yair R, Burns C E , Burns C G . (2019) En docardial Notch
signaling promotes cardiomyocyte proliferation in the regenerating zebrafish
heart through Wnt pathway antagonism. C ell Reports 26(3): 546-554.
6. Han P, Bloomekatz J, Ren J, Zhang R, Grinstein JD, Zhao L, Burns CG, Burns
CE, Anderson RM, and Chi NC. (2016) Coordinating cardiomyocyte interactions to
direct ventricular chamber morphogenesis. Nature 534: 700-704.
7. Jahangiri L, Sharpe M, Novikov N, González-Rosa JM, Borikova A, Nevis K,
Paffett-Lugassy N, Zhao L, Adams M, Guner-Ataman B, Burns CE, Burns CG. (2015)
The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial
differentiation from the zebrafish second heart field. Development 143: 113-122.
8. Mahmoud A, O’Meara C, Gemberling M, Zhao L, Bryant DM, Zheng RM, Gannon JB,
Cai L, Choi WY, Egaczyk GF, Burns CG, Burns CE, Macrae CA, Poss KD, Lee RT.
(2015) Nerves regulate cardiomyocyte proliferation and heart regeneration.
Developmental Cell 34: 387-399.
9. Harrison MR, Bussmann J, Huang Y, Zhao L, Osorio A, Burns CG, Burns CE, Sucov
HM, Siekmann AF and Lien CL. (2015) Chemokine guided angiogenesis directs
coronary vasculature formation in zebrafish. Developmental Cell 33(4): 442-454 .
10. Jang IH, Lu YF, Zhao L, Wenzel PL, Kume T, Datta SM, Arora N, Guiu J, Lagha
M, Kim PG, Schlaeger TM, Zon LI, Gigas A, Burns CE, Daley G. (2015) Notch1 acts
via Foxc2 to induce the endothelial to hematopoietic transition during embryonic
development. Blood 125(9): 1418- 14 26 .
11. Zhao L , Borikova AL, Ben-Yair R, Guner-Ataman B, Macrae CA, Lee RT, Burns
CG, Burns CE. (2014) Notch signaling regulates cardiomyocyte proliferation
during zebrafish heart regeneration. PNAS 111(4): 1403-1408.
12. Deacon DC, Nevis KR, Cashman TJ, Zhou Y, Zhao L , Washko D, Guner-Ataman B,
Burns CG, Burns CE. (2010) The miR-143-adducin3 pathway is essential for cardiac
chamber morphogenesis. Development 137(11): 1887-1896.
13. Zhao XY, Zhao L , Tian T, Zhang Y, Tong J, Zheng XF, Meng AM. (2010)
Interruption of cenph causes mitotic failure and embryonic death, and its
haploinsufficiency suppresses cancer in zebrafish. The Journal of Biological
Chemistry 285(36): 27924-27934.
14. Tian T, Zhao L , Zhao XY, Zhang M, Meng AM. (2009) A zebrafish gene trap
line expresses GFP recapturing expression pattern of foxj1b. Journal of Genetics
and Genomics 36(10): 581-589.
15. Tian T # , Zhao L # , Zhang M, Zhao XY, Meng AM. (2009) Both foxj1a and
foxj1b are implicated in left-right asymmetric development in zebrafish embryos.
Biochemical and Biophysical Research Communications 380(3): 537-542.
16. Zhao L , Zhao XY, Tian T, Lu QL, Nirma S, Wu D, Kuang Z, Zheng XF, Han YC,
Yang SY, Zhang CM, Meng AM. (2008) Heart-specific isoform of tropomyosin4 is
essential for heartbeat in zebrafish embryos. Cardiovascular Research 80(2):
200-208.