高珣 - 东南大学

个人简介

高珣，医学博士，副研究员，博士研究生导师，江苏省双创博士，江苏省卫生创新团队核心人才，东南大学仲英青年学者。主要从事呼吸危重症相关感染的致病机制、诊疗生物标志物和干预新策略的相关研究。近年来主持国家自然科学基金、江苏省自然科学基金等课题多项。以第一/通讯作者在Cellular and Molecular Immunology、Chest、Critical Care, Am J Respir Cell Mol Biol等一区杂志上发表SCI论文多篇，授权国家发明专利2项。曾应邀在香港免疫协会年会、新疆检验年会、安徽检验年会等国内外会议上做汇报；获得江苏省医学新技术引进奖（一等奖）等奖项二十余项。现任江苏省医学会检验分会青年委员、江苏省医学会微生物与免疫学分会委员、感染与免疫学组组员。

研究领域

呼吸危重症相关的生物标志物和诊疗新策略临床分子诊断学

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Cai S, Li X, Zhang C, Jiang Y, Liu Y, He Z, MaS, Yao Y, Wong CK, Wu G#, Wu G#, Gao X#.Inhibition of Interleukin-40 prevents multi-organ damage during sepsis by blocking NETosis. Crit Care. 2025 Jan 16;29(1):29. doi:10.1186/s13054-025-05257-2. 2. Zhang C, Cai S, Li Y, Xu X, Liu Y, Qiao H, WongC-K, Wu G, Jin H, Gao X. Elevation of Metrnβ and Its Association with Disease Activity in Systemic Lupus Erythematosus. Int. J. Mol. Sci. 2023; 24(17):13607.https://doi.org/10.3390/ijms241713607 3. Gao X, Chan PK, Wong KC, et al. Characterization of METRNbeta as a novel biomarker of Coronavirus disease 2019 severity and prognosis. Front Immunol. 2023;14:1111920. Published 2023 Jan 31.doi:10.3389/fimmu.2023.1111920 4. Gao X, Wu G, Tsang MS, Huang D, Lam CW, Wong CK. Novel insights into the role of anti-inflammatory IL-38 in immunity against infection. Cell Mol Immunol. 2022 Nov;19(11):1322-1324. doi:10.1038/s41423-022-00876-z. Epub 2022 Aug 16. PMID: 35974108; PMCID: PMC9379218. 5. Gao X, Leung TF, Wong GW, Ko WH, Cai M, He EJ, Chu IM,Tsang MS, Chan BC, Ling J, Fan X, Lu L, Lam CW, Wong CK. Meteorin-β/Meteorinlike/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma. Cell Mol Immunol. 2022 Feb;19(2):245-259. doi:10.1038/s41423-021-00803-8. 6. Gao X, Chan PKS, Lui GCY, et al. Interleukin-38ameliorates poly(I:C) induced lung inflammation: therapeutic implications inrespiratory viral infections. Cell Death Dis. 2021;12(1):53. Published2021 Jan 7. doi:10.1038/s41419-020-03283-2 7. Gao X, Liu Y, Xu F, Lin S, Song Z, Duan J, Yin Y, Cao J.Assessment of Apoptosis Inhibitor of Macrophage/CD5L as a Biomarker to Predict Mortality in the Critically Ill With Sepsis. Chest. 2019Oct;156(4):696-705. (被《Chest》作为必读文章推荐) 8. Gao X, Yan X, Yin Y, Lin X, Zhang Q, Xia Y, Cao J. Therapeutic Targeting of Apoptosis Inhibitor of Macrophage/CD5L in Sepsis.Am J Respir Cell Mol Biol. 2019 Mar;60(3):323-334. (被《AmJ Respir Cell Mol Biol》作为当期亮点推荐并配发评论文章“AIMing immunomodulation therapy at sepsis” ) 9. Gao X, Yan X, Zhang Q, Yin Y, Cao J. CD5L contributes to the pathogenesis of methicillin-resistant Staphylococcus aureus-induced pneumonia. Int Immunopharmacol. 2019 Jul;72:40-47.

学术兼职

江苏省医学会检验分会青年委员江苏省医学会微生物与免疫学分会委员感染与免疫学组组员