王丽虹 - 东南大学

个人简介

王丽虹，博士，研究员，博士生导师。东南大学医学院病理学与病理生理学学系党支部书记，病理生理学系主任。东南大学“发育与疾病相关基因”教育部重点实验室PI，江苏省重症医学重点实验室PI，江苏省病理生理学会理事，中国抗癌协会肿瘤标志专业委员会-非编码RNA与肿瘤研究专家委员会委员。主要从事非编码RNA在乳腺癌中的作用机制研究以及肿瘤耐药性分子标志物的识别研究。先后以第一作者或通讯作者发表SCI论文20余篇，主持国家自然科学基金项目2项，省市级等各类科研课题10余项。

研究领域

主要从事非编码RNA在乳腺癌中的作用机制研究以及肿瘤耐药性分子标志物的识别研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

（1） Jiani Xing, Haizhou Liu, Wei Jiang, Lihong Wang. LncRNA-Encoded Peptide: Functions and Predicting Methods. Front Oncol. 2021 Jan 14; 10: 622294. （2） Zhou, SH, Huang, YE, Liu, HZ, Zhou, X, Yuan, MQ, Hou, F, Wang, LH, Jiang, W.Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks. Mol Ther Nucleic Acids. 2021 Jan 1; 23: 682-690. （3） Shuyuan Wang, Shunheng Zhou, Haizhou Liu, Qianqian Meng, Xueyan Ma, H Liu, Lihong Wang, Wei Jiang. ncRI:a manually curated database for experimentally validated non-coding RNAs in inflammation. BMC Genomics. 2020 Jun 1;21(1):380. （4） Haizhou Liu, Xu Zhou, Mengqin Yuan, Shunheng Zhou, Yu-E Huang, Fei Hou, Xiaofeng Song, Lihong Wang, Wei Jiang. ncEP: A Manually Curated Database for Experimentally Validated ncRNA-encoded Proteins or Peptides. J Mol Biol. 2020 May 15; 432 (11): 3364-3368. （5） Yu-E Huang, Shunheng Zhou, Haizhou Liu, Xu Zhou, Mengqin Yuan, Fei Hou, Lihong Wang, Wei Jiang. Identification of drug resistance associated ncRNAs based on comprehensive heterogeneous network. 2020 Feb 15; 243:117256. （6） Lihong Wang, Tian Luan, Shunheng Zhou, Jing Lin, Yue Yang, Wei Liu, Xiao Tong, Wei Jiang. LncRNA HCP5 promotes triple negative breast cancer progression as a ceRNA to regulate BIRC3 by sponging miR-219a-5p. Cancer Med. 2019 Aug; 8(9):4389-4403. （7） Leiming Jiang, Xuexin Yu, Xueyan Ma, Haizhou Liu, Shunheng Zhou, Qianqian Meng, Lihong Wang, Wei Jiang. Identification of transcription factor-miRNA-IncRNA feed-forward loops in breast cancer subtypes. Comput Biol Chem.2019 Feb 78:1-7. Meng （8） Shunheng Zhou, Lihong Wang, Qian Yang, Haizhou Liu, Qianqian, Leiming Jiang, Shuyuan Wang, Wei Jiang. Systematical analysis of lncRNA-mRNA competing endogenous RNA network in breast cancer subtypes. Breast Cancer Research and Treatment 2018 Jun;169(2):267-275. （9） Tian Luan, Ximei Zhang, Shuyuan Wang, Jing Lin, Weiwei An, Weiguang Yuan, Huilong Cai, Qingyuan Zhang, Lihong Wang. Long non-coding RNA MIAT promotes breast cancer progression and functions as ceRNA to regulate DUSP7 expression by sponging miR-155. Oncotarget. 2017 Jul 12;8(44):76153-76164 （10） Jing Lin, Wei Liu, Tian Luan, Lili Yuan, Wei Jiang, Huilong Cai, Weiguang Yuan, Yuwen Wang, Qingyuan Zhang, Lihong Wang. High expression of PU.1 is correlation with Her-2 and shorter survival in breast cancer patients. Oncology Letters. 2017 14: 8220-8226. （11） Weisha Liu, Shuyuan Wang, Shunheng Zhou, Feng Yang, Wei Jiang, Qingyuan Zhang, Lihong Wang. A systems biology approach to identify microRNAs contributing to cisplatin resistance in human ovarian cancer cells. Mol Biosyst. 2017 Oct 24;13(11):2268-2276. （12） Enyu Dai, Feng Yang, Jing Wang, Xu Zhou, Qian Song, Weiwei An, Lihong Wang, Wei Jiang. ncDR: a comprehensive resource of non-coding RNAs involved in drug resistance. Bioinformatics. 2017 Dec 15; 33 (24): 4010-4011.

学术兼职

东南大学医学院病理学与病理生理学学系党支部书记，病理生理学系主任。东南大学“发育与疾病相关基因”教育部重点实验室PI，江苏省重症医学重点实验室PI，江苏省病理生理学会理事，中国抗癌协会肿瘤标志专业委员会-非编码RNA与肿瘤研究专家委员会委员。