Kaialy, Waseem - University of Wolverhampton - Faculty of Science & Engineering

个人简介

Dr Kaialy (BPharm, MPhil, PhD, FHEA) obtained his BPharm degree in Damascus University where he was awarded five Academic-Excellence awards (2003 to 2007) and an overseas summer training scholarship award (T3 Pharmaceuticals, Cairo, Egypt). He graduated on 2007 with the honour of the Top Graduate student. He has been a qualified pharmacist since 2007 and worked as a pharmacy manager from 2007 to 2008. Then, he worked as a teaching assistant in the Pharmaceutics and Pharmaceutical Technology Department at the School of Pharmacy, University of Damascus, Syria from 2008 to 2009. He completed his PhD studies on pharmaceutics-drug delivery in 2013 at the University of Kent (UK) in collaboration with Pfizer (Sandwich, UK). He held a research associate postdoctoral post at University in Kent, UK (2013) where he did consultancies for Teva Pharmaceutical Industries LTD (USA). Waseem has been a Visiting Research at Luleå University of Technology (Sweden), holding an ERAS Fellowship (University of Wolverhampton), and a fellowship of the higher education academy (FHEA). In 2014, he was appointed as a Lecturer/Senior lecturer in pharmaceutics at University of Wolverhampton, UK. Dr Kaialy has an extended knowledge in pharmaceutical science and a significant experience of high-quality teaching/supervision in Higher Education at UG and PG level since 2008. He is currently involved in a variety of research projects and collaborates with academic and industrial partners within the UK and internationally. The overall goal of his research is to improve drug delivery through understanding and enhancing the physicochemical, mechanical, and biopharmaceutical properties of pharmaceuticals. Of particular interest is particle/chemical engineering to improve the (i) aerosolisation performance of dry powder inhalers, (ii) solubility and dissolution rate of poorly soluble drugs, and (iii) and tabletability of poorly compactible drugs.

研究领域

Pharmaceutical Sciences, Pharmaceutics, Drug Delivery, Inhalation, Solid Dosage Forms, Particle Engineering. Waseem’s ongoing research topics include particle engineering of excipients and drugs in order to improve their physicochemical, physicomechanical and biopharmaceutical properties for better oral and pulmonary delivery. The aspiration of his combined expertise in different drug delivery areas is to deliver ‘proof of concept’ for specific engineered particles and particle engineering strategies that will ultimately attain ‘concept of clinic’ approach to development of these excipients.

近期论文

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S Shojaee, A Nokhodchi, I Cumming, A Alhalaweh, Waseem Kaialy. Investigation of drug release from PEO tablet matrices in the presence of vitamin E as antioxidant. Current drug delivery, in press. S Shojaee, P Emami, A Mahmood, Y Rowaiye, A Dukulay, Waseem Kaialy, I Cumming, A Nokhodchi. An Investigation on the Effect of Polyethylene Oxide Concentration and Particle Size in Modulating Theophylline Release from Tablet Matrices. AAPS PharmSciTech, in press. Waseem Kaialy, A Nokhodchi. Dry powder inhalers: Physicochemical and aerosolization properties of several size-fractions of a promising alterative carrier, freeze-dried mannitol (2015). European Journal of Pharmaceutical Sciences, 28, 56–67. Shojaee S, Waseem Kaialy, K I Cumming, A Nokhodchi. Comparative Evaluation of Drug Release from Aged Prolonged Polyethylene Oxide Tablet Matrices: Effect of Excipient and Drug Type. Pharmaceutical development and technology, in press. Waseem Kaialy, Maniruzzaman M, Shojaee S, Nokhodchi A (2014). Antisolvent precipitation of novel xylitol-additive crystals to engineer tablets with improved biopharmaceutical performance. International Journal of Pharmaceutics, 477, 282–293. Elsayed A, d, Mahmoud S, Al-Dadah R, Bowen J, Waseem Kaialy (2014). Experimental and Numerical Investigation of The Effect of Pellet Size on the adsorption Characteristics of Activated Carbon/Ethanol. Energy Procedia, 61, 2327 – 2330. Alhalaweh A, Alzghoul A, Waseem Kaialy, Mahlin D, Bergström CAS (2014). Computational Predictions of Glass-Forming Ability and Crystallization Tendency of Drug Molecules. Molecular Pharmaceutics, 11, 3123-3132. Waseem Kaialy, Larhrib H, Shojaee S, Nokhodchi A (2014). An approach to engineer paracetamol crystals by antisolvent crystallization technique in presence of various additives for direct compression. International journal of pharmaceutics, 464, 53-64.