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个人简介

Dr Antoun graduated with an honours degree in Pharmacy in 1997 and went to undertake a PhD studying the effect of initiation factors on protein synthesis in Uppsala University, Sweden. After completing his PhD in 2005, He joined the school of Cancer sciences, University of Birmingham as a research Fellow with particular interest on the effect of immunological factors such as NKG2D ligands on the clinical outcome of Stem cell Transplant. Dr Antoun worked as a clinical Pharmacist in Dudley and Walsall mental health trust. Dr Antoun came to the University of Wolverhampton in 2016 to take up the post of Senior Lecturer in Pharmacology.

研究领域

The effect of Lithium in treating patients suffering from Bipolar and renal complications Comparison of the effect of Lithium versus quetiapine on bipolar clinical outcomes Interest in hospital admissions related to non-adherence to antipsychotics medicines Interest in the development of novel approaches for the teaching and learning in the pharmacy school.

近期论文

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The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation. Antoun A, Vekaria D, Salama RA, Pratt G, Jobson S, Cook M, Briggs D, Moss P. Br J Haematol. 2012 Dec;159(5):589-98. An NKG2D-mediated human lymphoid stress surveillance response with high interindividual variation. Shafi S, Vantourout P, Wallace G, Antoun A, Vaughan R, Stanford M, Hayday A. Sci Transl Med. 2011 Dec 14;3(113):113ra124. Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations. Antoun A, Jobson S, Cook M, O'Callaghan CA, Moss P, Briggs DC. Hum Immunol. 2010 Jun;71(6):610-20. Ethnic variability in human leukocyte antigen-E haplotypes. Antoun A, Jobson S, Cook M, Moss P, Briggs D. Tissue Antigens. 2009 Jan;73(1):39-45. Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting. Pavlov MY, Antoun A, Lovmar M, Ehrenberg M. EMBO J. 2008 Jun 18;27(12):1706-17. How initiation factors maximize the accuracy of tRNA selection in initiation of bacterial protein synthesis. Antoun A, Pavlov MY, Lovmar M, Ehrenberg M. Mol Cell. 2006 Jul 21;23(2):183-93. How initiation factors tune the rate of initiation of protein synthesis in bacteria. Antoun A, Pavlov MY, Lovmar M, Ehrenberg M. EMBO J. 2006 Jun 7;25(11):2539-50. A time-resolved investigation of ribosomal subunit association. Hennelly SP, Antoun A, Ehrenberg M, Gualerzi CO, Knight W, Lodmell JS, Hill WE. J Mol Biol. 2005 Mar 11;346(5):1243-58.

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