Goggolidou, Paraskevi - University of Wolverhampton - Faculty of Science & Engineering

个人简介

Paraskevi graduated from the 3rd High School of Mytilene, Lesvos, Greece with 19.4/20 in the National Apolytirion (with 4 A-levels in Biology, Chemistry, Physics and Greek). Before completion of her A levels, she had secured a position in the Molecular Genetics BSc at King’s College London, where she graduated with a 2:1 in June 2001. She then embarked on a PhD in the prestigious Weatherall Institute of Molecular Medicine, after having obtained a highly competitive Medical Research Council (MRC) PhD studentship to work on the regulation of the mouse alpha globin cluster. This was followed by a post-doctoral career development fellowship at MRC Harwell and since 2010, she has obtained independent positions in academia, focusing her research on understanding the genetic mechanisms that underlie rare diseases, with the ultimate aim of impacting on disease prognosis and finding pharmacological treatments for them

研究领域

Cilia, Molecular Genetics, Gene expression analysis and networks

近期论文

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Goggolidou P. and Wilson P.D. (2016) Novel biomarkers in kidney disease: the roles of cilia, Wnt signalling and ATMIN in polycystic kidney disease. Biochemical Society Transactions, 44(6), 1745-1751. Goggolidou P., Hadjirin N.F., Bak A., Papakrivopoulou E., Hilton H., Norris D.P., Dean C.H. (2014) Atmin mediates kidney morphogenesis by modulating Wnt signalling. Human Molecular Genetics, 23(20), 5303-5316. Goggolidou P., Stevens S., Agueci F., Wheway G., Grimes D. et al. (2014) ATM-interactor (ATMIN) is a transcriptional regulator of both lung morphogenesis and ciliogenesis. Development, 141(20), 3966-3977. Yusuf B J, Goggolidou P, Milne T, Abba A A, Bakari A G, Sa'idu A, Dutse A I, Gwaram B A, Ashfaq K, Abubakar S A. (2014) Validity of new flow cytometric protocol in diagnosis of low-grade myelodysplastic syndromes. Sub-Saharan Afr J Med, 1, 40-47. Goggolidou P. (2014) Wnt and planar cell polarity signalling in cystic renal disease. Organogenesis, 10(1), 86-95. Goggolidou P., Soneji S., Powles-Glover N., Williams D., Sethi S., Baban D., Simon M.M., Ragoussis I., Norris D.P. (2013) A chronological expression profile of gene activity during embryonic mouse brain development. Mammalian Genome, 24(11-12), 459-472. Yates L.L., Papakrivopoulou J., Long D.A., Goggolidou P., O.Connelly J., Woolf A.S., Dean C.H. (2010) The planar cell polarity gene Vangl2 is required for mammalian kidney branching morphogenesis and glomerular maturation. Human Molecular Genetics, 19 (23), 4663-4676. Guzman-Ayala M., Lee K.L., Mavrakis K.J., Goggolidou P., Norris DP., Episkopou V. (2009) Graded Smad2/3 activation is converted directly into levels of target gene expression in Embryonic Stem Cells. PLOS ONE, 4(1), e4268. Ermakov A., Stevens J.L., Whitehill E., Robson J.E., Pieles G., Brooker D., Goggolidou P., Powles-Glover N., Hacker T., Young S.R., Dear N., Hirst E., Tymowska-Lalanne S., Briscoe J., Bhattacharya S., Norris D.P. (2009) Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular and limb development. Developmental Dynamics, 238 (3), 581-94.