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个人简介

Degree: Glasgow University Cell Biology (1st Class) PhD: Dundee University Post-Doctoral experience (USA and MRC-HGU, UK) Currently: Senior Lecturer in Biomedical Science

研究领域

DNA Repair, Cytoskeleton, Colorectal Cancer, Oesophageal and Ovarian Cancer, Aspirin analogues

近期论文

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Claudius, A-K., Kankipati, C.S., Kilari, R.S., Hassan, S., Guest, K., Russell, S.T., Perry, C.J., Stark, L. and I.D. Nicholl. (2014) Identification of aspirin analogues that repress NF-kB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo Oncology Reports 32: 1670-1680. Prabhu,S., Dennison, S.R., Lea, R., Snape, T.J., Nicholl, I.D., Radecka, I., and F. Harris. (2013) Anionic antimicrobial and anticancer peptides from plants. Critical Reviews in Plant Science, 32(5):303-320. Deb, J., Dibra H.K., Shan,S., Rajan,S., Manneh, J., Kankipati, C.S., Perry, C.J. and I.D.Nicholl. (2011) Activity of aspirin analogues and vanillin toward a human colorectal cancer cell line. Oncology Reports, 26: 557-565. Barnetson, R.A., Tenesa, A., Farrington, S.M., Nicholl, I.D. , Cetnarskyj, R., Porteous, M.E., Campbell, H., and M.G. Dunlop. (2006) Identification of Carriers of Mutant DNA Mismatch Repair Genes in Patients with Colon Cancer. The New England Journal of Medicine Vol. 354:2751-2763. Cerami, C., Founds, H., Nicholl, I.D., Mitsuhashi, T., Giordano, D., Van Patten, S., Finch, G., Donnelly, T., Lee, A., Al-Abed, Y., Vlassara, H.V., Bucala, R. and A. Cerami. (1997) Tobacco Smoke is a Source of Toxic Reactive Glycation Products. Proc. Natl. Acad. Sci. USA 94, 13915-13920. Nicholl, I.D., Nealon, K., and M. K. Kenny. (1997) Reconstitution of Human Base Excision Repair with Purified Proteins. Biochemistry 36, 7557-7566. Nicholl, I.D. and R.A. Quinlan. (1994) Chaperone Activity of a-Crystallins Modulates Intermediate Filament Assembly. EMBO J. 13, 945-953.

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