个人简介
学习工作经历
2023.09-至今,
重庆大学,药学院(创新药物研究中心),副教授,博士生导师;
2020.09-2023.08,
重庆大学,药学院(创新药物研究中心),弘深青年教师;
2017.07-2020.06,
北京大学,化学与分子工程学院,博士后,合作导师:陈鹏 教授;
2012.09-2017.07,
北京大学,前沿交叉学科研究院,博士,导师:陈鹏 教授;
2008.09-2012.07,
北京大学,生命科学学院,学士;
研究领域
药物化学生物学,蛋白质化学生物学
DNA编码分子库(DNA-encoded library, DEL)的新型筛选技术研究;
蛋白质的位点特异性配体筛选策略研究;
蛋白质的选择性修饰与共价抑制剂研究。
近期论文
查看导师新发文章
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1. Zhang Juan#; Liu Jinlu; Li Xianfeng; Ju Yunzhu; Li Yangfeng; Zhang Gong*; Li Yizhou*, Unexpected Cyclization Product Discovery from the Photoinduced Bioconjugation Chemistry between Tetrazole and Amine, Journal of the American Chemical Society, 2024, 146(3), 2122-2131
2. Zhang Gong, Zhang Juan, Gao Yuting, Li Yangfeng*, Li Yizhou*, Strategies for targeting undruggable targets, Expert Opinion on Drug Discovery, 2022, 17, 55-69.
3. Zhang Juan, Li Xianfeng, Wei Haimei, Li Yangfeng, Zhang Gong*, Li Yizhou*, Sequential DNA-encoded building block fusion for the construction of polysubstituted pyrazoline core libraries, Organic Letters, 2021, 23, 8429-8433
4. Zhu Rongfeng#, Zhang Gong#, Jing Miao, Han Yu, Li Jiaofeng, Li Yulong, Chen Peng R.*, Genetically encoded formaldehyde sensors inspired by a protein intra-helical crosslinking reaction, Nature Communications, 2021, 12, 581.
5. Zhang Gong#, Li Jie#, Xie Ran, Fan Xinyuan, Liu Yanjun, Zheng Siqi, Ge Yun, Chen Peng R.*, Bioorthogonal chemical activation of kinases in living systems, ACS Central Science, 2016, 2, 325-331. (Highlighted by Chemical & Engineering News, 2016, 94(19), 5)
6. Zhang Gong#, Zheng Siqi#, Liu Haiping, Chen Peng R.*, Illuminating biological processes through site-specific protein labeling, Chemical Society Reviews, 2015, 44, 3405-3417.
7. Zheng Siqi#, Zhang Gong#, Li Jie, Chen Peng R.*, Monitoring endocytic trafficking of anthrax lethal factor by precise and quantitative protein labeling. Angewandte Chemie International Edition, 2014, 53, 6449-6453.